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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
172 Results for "
Quinone Reductase
" in MedChemExpress (MCE) Product Catalog:
Products (172)
172 Results for "Quinone Reductase" in MCE Product Catalog:
18
Category:
Melilotus officinalis (L.) Pall. Coumarins Leguminosae Extract Phenylpropanoids Plants Disease Research Fields Biological Pesticide Research Cancer Agricultural Research
Target:
12
12 Cited Publications
Synonyms: 6PPD-Quinone
Category:
Alkaloids Quinones Other Alkaloids Other Diseases Benzene Quinones Endogenous metabolite Disease Research Fields
Target:
10
10 Cited Publications
Synonyms: PQQ; Methoxatin
Category:
Quinones Microorganisms Animals Benzene Quinones Endogenous metabolite Disease Research Fields Inflammation/Immunology
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10
10 Cited Publications
Synonyms: PQQ disodium salt; Methoxatin disodium salt
Category:
Quinones Microorganisms Benzene Quinones Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
5
5 Cited Publications
Synonyms: Triptycene-1,4-Quinone
Research Areas:
INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 specifically blocks targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site and is an effective inhibitor of CN-NFAT signaling .
3
3 Cited Publications
Target:
Research Areas:
2-HBA is a potent inducer of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) which can also activate caspase-3 and caspase-10.
2
2 Cited Publications
2
2 Cited Publications
Target:
Research Areas:
FC9402 is a potent and selective sulfide quinone oxidoreductase (SQOR) inhibitor extracted from patent WO 2020/146636 A1. FC9402 attenuates TAC-induced cardiomyocyte hypertrophy and left ventricle (LV) fibrosis. FC9402 can be used for cardiovascular regulation .
2
2 Cited Publications
Cat. No.: HY-P80251
Synonyms: DIA4, NMOR1, NQO1, NAD(P)H dehydrogenase [Quinone] 1, AzoReductase, DT-diaphorase, Menadione Reductase, NAD(P)H:Quinone oxidoReductase 1, PhylloQuinone Reductase, Quinone Reductase 1, DTD, QR1
2
Target:
Research Areas:
S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 induces autophagy and inhibits QR2-mediated ROS production .
1
1 Cited Publications
Cat. No.: HY-N4168A
CAS No.: 123410-65-1
Synonyms: 5-O-Caffeoylquinic acid methyl ester
Target:
1
1 Cited Publications
Cat. No.: HY-N1551
CAS No.: 76843-23-7
Category:
Quinones Diterpenoids Plants Naphthalene Quinones Labiatae Extract Vachellia nilotica (L.) P. J. H. Hurter & Mabb.
Target:
1
1 Cited Publications
Cat. No.: HY-W176199
CAS No.: 3421-08-7
Research Areas:
DPPD-Q is a quinone derivative of p-phenylenediamine antioxidants and an analog of DTPD-Q (HY-163650). DPPD-Q is identified as a major sewage treatment plant effluent .
1
1 Cited Publications
Cat. No.: HY-W728085
CAS No.: 68054-78-4
Research Areas:
CPPD-Q is a PPD-quinone. CPPD-Q induces increased intestinal permeability and oxidative stress in C. elegans. CPPD-Q targets HMP-2 and ACS-22 to regulate the intestinal barrier, and targets SOD-3 and GST-4 to mediate oxidative stress responses. CPPD-Q induces reactive oxygen species (ROS) production through quinone-mediated redox cycling, and exhibits oxidative potential through dithiothreitol depletion. CPPD-Q is used in research related to intestinal diseases .
1
1 Cited Publications
Cat. No.: HY-N1066
CAS No.: 274675-25-1
Category:
Flavonoids Chalcones Humulus lupulus L. Moraceae Extract Phenols Polyphenols Plants Disease Research Fields Cancer
Target:
1
1 Cited Publications
Cat. No.: HY-P74405A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NQO1; DHQU; Prev. NMOR1; NAD(P)H Dehydrogenase, Quinone 1; Prev. DIA4; NAD(P)H-Quinone OxidoReductase; DT-Diaphorase; NAD(P)H:Quinone Acceptor OxidoReductase Type 1; QR1; NAD(P)H:Menadione OxidoReductase 1; DTD; NAD(P)H:Quinone OxiReductase; NAD(P)H Dehyd
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-N9942
CAS No.: 23027-91-0
1
1 Cited Publications
Research Areas:
KL1333, a derivative of β-lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear cultures .
1
1 Cited Publications
Cat. No.: HY-W754777
CAS No.: 68054-73-9
Target:
Research Areas:
IPPD-Q is a p-phenylenediamine quinone and also Environmental pollutant. IPPD-Q can be present in tires, fine particulate matter and urban water bodies. IPPD-Q increases the activities of antioxidant enzymes (SOD, CAT), alters photosynthesis and energy metabolism pathways, and changes gene expression and metabolic profiles. IPPD-Q exhibits phytotoxic effects. IPPD-Q shows acute toxicity to zebrafish embryos and reduces their survival rate .
1
Target:
Research Areas:
PQQ-trimethylester (PQQ-TME) is a synthetic compound that is a trimethylester derivative of pyrroloquinoline quinone (PQQ). PQQ-trimethylester has twice the blood-brain barrier permeability of PQQ (HY-100196) in vitro. In addition, PQQ-trimethylester shows strong inhibitory activity against α-synuclein, amyloid β1-42 (Aβ1-42) and prion protein fibrillation. PQQ-trimethylester can be used in the study of neurodegenerative diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
