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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
RSV-A
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "RSV-A" in MCE Product Catalog:
5
Clesrovimab (MK-1654) is a humanized IgG1 monoclonal antibody targeting the respiratory syncytial virus (RSV) protein F. Clesrovimab binds to pre-fusion and post-fusion forms of RSV-A fusion protein with high affinity, with corresponding KD values of 71 pM and 480 pM, respectively. Clesrovimab is applicable for the research of RSV infection .
3
3 Cited Publications
PC786 is an inhaled respiratory syncytial virus (RSV) L protein polymerase inhibitor. PC786 demonstrates potent antiviral activity against RSV-A (IC50 <0.09 to 0.71 nM) and RSV-B (IC50, 1.3 to 50.6 nM) .
1
1 Cited Publications
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
RSVA405 is a potent, orally active activator of AMPK, with an EC50 of 1 μM. RSVA405 facilitates CaMKKβ-dependent activation of AMPK, inhibits mTOR, and promotes autophagy to increase Aβ degradation. RSVA405 has anti-inflammatory effects through the inhibition of STAT3 function. RSVA405 can also be used for the research of obesity .
Cat. No.: HY-156442
CAS No.: 2241027-61-0
Target:
Research Areas:
MEDS433 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 1.2 nM. MEDS433 exerts a potent antiviral activity against RSV-A and RSV-B in the one-digit nanomolar range. MEDS433 induces the expression of antiviral proteins encoded by interferon stimulated genes (ISGs) able to reduce RSV replication .
Cat. No.: HY-103238R
CAS No.: 140405-36-3
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
RSVA405 (Standard) is the analytical standard of RSVA405 (HY-103238). This product is intended for research and analytical applications. RSVA405 is a potent, orally active activator of AMPK, with an EC50 of 1 μM. RSVA405 facilitates CaMKKβ-dependent activation of AMPK, inhibits mTOR, and promotes autophagy to increase Aβ degradation. RSVA405 has anti-inflammatory effects through the inhibition of STAT3 function. RSVA405 can also be used for the research of obesity .
Cat. No.: HY-169313
CAS No.: 2994287-06-6
HRSV/HMPV-IN-1 (compound 3) is a HRSV/HMPV inhibitor with the EC50 values of ＜ 0.2 μM and ＜ 0.5 μM for human RSV-A and human MPV A2 TN/94-49, respectively. HRSV/HMPV-IN-1 can be used for study of bronchiolitis and pneumonia .
Cat. No.: HY-P705638
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Human respiratory syncytial virus (RSV) (A2) Prefusion glycoprotein F/ RSV-preF Protein
Species:
Virus
Source:
CHO
Cat. No.: HY-102038R
CAS No.: 1902114-15-1
Target:
Research Areas:
PC786 (Standard) is the analytical standard of PC786 (HY-102038). This product is intended for research and analytical applications. PC786 is an inhaled respiratory syncytial virus (RSV) L protein polymerase inhibitor. PC786 demonstrates potent antiviral activity against RSV-A (IC50 <0.09 to 0.71 nM) and RSV-B (IC50, 1.3 to 50.6 nM) .
Cat. No.: HY-189661
CAS No.: 3136661-66-7
Target:
Research Areas:
RSV-IN-15 is a selective inhibitor of the RSV RNA-dependent RNA polymerase PRNTase domain. RSV-IN-15 blocks polymerase-dependent RNA synthesis through allosteric binding. RSV-IN-15 exhibits antiviral EC50 = 37 nM against the RSV‑A Long strain in Hep‑2 cells, reduces polymerase-dependent reporter gene activity, and inhibits RSV RNA synthesis. RSV-IN-15 can be used for research on respiratory syncytial virus infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
