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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
Ramipril
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "Ramipril" in MCE Product Catalog:
2
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Ramipril (HOE-498) is an orally active angiotensin-converting enzyme (ACE) inhibitor with blood-brain barrier permeability, and it is metabolized in vivo to the active metabolite Ramiprilat (HY-A0115). Ramipril has antioxidant, vasoprotective, and anti-atherosclerotic effects. Ramipril reduces the degradation of angiotensin II and bradykinin, downregulates TGF-beta/CTGF/fibronectin/α-SMA, and inhibits pancreatic/cardiac fibrosis. Ramipril improves glucose tolerance and insulin secretion, and reduces weight gain/appetite. Ramipril sensitizes mast cells, enhances FcεRI histamine release/degranulation, aggravates IgE allergic reactions, and downregulates the bradykinin receptor. Ramipril improves vascular endothelial relaxation function in spontaneously hypertensive rats. Ramipril alleviates Oxaliplatin (HY-17371)-induced acute hyperalgesia in mice. Ramipril can be used in research related to diseases such as type 2 diabetes, rheumatoid arthritis, allergy, and hypertension .
Cat. No.: HY-A0115
CAS No.: 87269-97-4
Synonyms: HOE 498 diacid; Ramipril diacid
Research Areas:
Ramiprilat (HOE 498 diacid), an active metabolite of Ramipril, is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with a Ki value of 7 pM. Ramiprilat has acute antlhypertensive effect. Ramiprilat can be used for high blood pressure and heart failure research .
Cat. No.: HY-B0279S
CAS No.: 1132661-86-9
Synonyms: HOE-498-d5
Ramipril-d5 (HOE-498-d5) is the deuterated-labeled Ramipril (HY-B0279). Ramipril (HOE-498) is an orally active angiotensin-converting enzyme (ACE) inhibitor with blood-brain barrier permeability, and it is metabolized in vivo to the active metabolite Ramiprilat (HY-A0115). Ramipril has antioxidant, vasoprotective, and anti-atherosclerotic effects. Ramipril reduces the degradation of angiotensin II and bradykinin, downregulates TGF-beta/CTGF/fibronectin/α-SMA, and inhibits pancreatic/cardiac fibrosis. Ramipril improves glucose tolerance and insulin secretion, and reduces weight gain/appetite. Ramipril sensitizes mast cells, enhances FcεRI histamine release/degranulation, aggravates IgE allergic reactions, and downregulates the bradykinin receptor. Ramipril improves vascular endothelial relaxation function in spontaneously hypertensive rats. Ramipril alleviates Oxaliplatin (HY-17371)-induced acute hyperalgesia in mice. Ramipril can be used in research related to diseases such as type 2 diabetes, rheumatoid arthritis, allergy, and hypertension .
Cat. No.: HY-B0279S1
CAS No.: 2673269-81-1
Synonyms: HOE-498-d3
Ramipril-d3 (HOE-498-d3) is the deuterated-labeled Ramipril (HY-B0279). Ramipril (HOE-498) is an orally active angiotensin-converting enzyme (ACE) inhibitor with blood-brain barrier permeability, and it is metabolized in vivo to the active metabolite Ramiprilat (HY-A0115). Ramipril has antioxidant, vasoprotective, and anti-atherosclerotic effects. Ramipril reduces the degradation of angiotensin II and bradykinin, downregulates TGF-beta/CTGF/fibronectin/α-SMA, and inhibits pancreatic/cardiac fibrosis. Ramipril improves glucose tolerance and insulin secretion, and reduces weight gain/appetite. Ramipril sensitizes mast cells, enhances FcεRI histamine release/degranulation, aggravates IgE allergic reactions, and downregulates the bradykinin receptor. Ramipril improves vascular endothelial relaxation function in spontaneously hypertensive rats. Ramipril alleviates Oxaliplatin (HY-17371)-induced acute hyperalgesia in mice. Ramipril can be used in research related to diseases such as type 2 diabetes, rheumatoid arthritis, allergy, and hypertension .
Cat. No.: HY-A0115S1
CAS No.: 2021255-43-4
Cat. No.: HY-A0115R
CAS No.: 87269-97-4
Synonyms: HOE 498 diacid (Standard); Ramipril diacid (Standard)
Category:
Cat. No.: HY-Z8381
CAS No.: 108731-95-9
Research Areas:
Ramipril diketopiperazine is an impurity in the ACE inhibitor Ramipril (HY-B0279) .
Cat. No.: HY-B0279R
CAS No.: 87333-19-5
Synonyms: HOE-498 (Standard)
Ramipril (Standard) (HOE-498 (Standard)) is the analytical standard of Ramipril (HY-B0279). This product is intended for research and analytical applications. Ramipril (HOE-498) is an orally active angiotensin-converting enzyme (ACE) inhibitor with blood-brain barrier permeability, and it is metabolized in vivo to the active metabolite Ramiprilat (HY-A0115). Ramipril has antioxidant, vasoprotective, and anti-atherosclerotic effects. Ramipril reduces the degradation of angiotensin II and bradykinin, downregulates TGF-beta/CTGF/fibronectin/α-SMA, and inhibits pancreatic/cardiac fibrosis. Ramipril improves glucose tolerance and insulin secretion, and reduces weight gain/appetite. Ramipril sensitizes mast cells, enhances FcεRI histamine release/degranulation, aggravates IgE allergic reactions, and downregulates the bradykinin receptor. Ramipril improves vascular endothelial relaxation function in spontaneously hypertensive rats. Ramipril alleviates Oxaliplatin (HY-17371)-induced acute hyperalgesia in mice. Ramipril can be used in research related to diseases such as type 2 diabetes, rheumatoid arthritis, allergy, and hypertension .
Cat. No.: HY-B0279S2
CAS No.: 1132661-83-6
Synonyms: HOE-498-d4
Ramipril-d4 (HOE-498-d4) is the deuterated-labeled Ramipril (HY-B0279). Ramipril (HOE-498) is an orally active angiotensin-converting enzyme (ACE) inhibitor with blood-brain barrier permeability, and it is metabolized in vivo to the active metabolite Ramiprilat (HY-A0115). Ramipril has antioxidant, vasoprotective, and anti-atherosclerotic effects. Ramipril reduces the degradation of angiotensin II and bradykinin, downregulates TGF-beta/CTGF/fibronectin/α-SMA, and inhibits pancreatic/cardiac fibrosis. Ramipril improves glucose tolerance and insulin secretion, and reduces weight gain/appetite. Ramipril sensitizes mast cells, enhances FcεRI histamine release/degranulation, aggravates IgE allergic reactions, and downregulates the bradykinin receptor. Ramipril improves vascular endothelial relaxation function in spontaneously hypertensive rats. Ramipril alleviates Oxaliplatin (HY-17371)-induced acute hyperalgesia in mice. Ramipril can be used in research related to diseases such as type 2 diabetes, rheumatoid arthritis, allergy, and hypertension .
Cat. No.: HY-137361
CAS No.: 108736-10-3
Synonyms: Ramipril diketopiperazine acid
Research Areas:
Ramiprilat diketopiperazine (Ramipril diketopiperazine acid; Impurity K) is an impurity of Ramiprilat (HY-A0115). Ramiprilat, an active metabolite of Ramipril (HY-B0279), is a potent and orally active angiotensin converting enzyme (ACE) inhibitor .
Cat. No.: HY-Z6860
CAS No.: 108313-11-7
Synonyms: Ramipril methyl ester
Target:
Research Areas:
Ramipril impurity 1 (Ramipril methyl ester) is an impurity of Ramipril.
Cat. No.: HY-Z6861
CAS No.: 295328-72-2
Synonyms: Ramipril isopropyl ester
Target:
Research Areas:
Ramipril impurity 6 (Ramipril isopropyl ester) is an impurity of Ramipril.
Cat. No.: HY-Z8384
CAS No.: 1246253-05-3
Synonyms: ent-Ramipril
Target:
Research Areas:
Ramipril impurity 2 (ent-Ramipril) is an impurity of Ramipril.
Cat. No.: HY-Z18062
CAS No.: 1309040-96-7
Synonyms: Ramipril impurity L
Target:
Research Areas:
Ramipril impurity 3 (Ramipril impurity L) is an impurity of Ramipril.
Cat. No.: HY-W778915
CAS No.: 151387-05-2
Synonyms: Ramipril impurity O
Target:
Research Areas:
Ramipril impurity 4 (Ramipril impurity O) is an impurity of Tadalafil.
Cat. No.: HY-A0115S2
Synonyms: Ramiprilat-d4 hydrochloride
Cat. No.: HY-W008300
CAS No.: 87269-87-2
Target:
Research Areas:
Ramipril impurity 5 is an impurity of Ramipril.
Cat. No.: HY-B0279A
CAS No.: 129939-63-5
Target:
Research Areas:
Ramipril impurity 11 is an impurity of Ramipril.
Cat. No.: HY-Z8382
CAS No.: 104195-90-6
Target:
Research Areas:
Ramipril impurity 8 is an impurity of Ramipril.
Cat. No.: HY-Z8383
CAS No.: 129939-65-7
Target:
Research Areas:
Ramipril impurity 9 is an impurity of Ramipril.
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
