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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
Reticulocytes
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "Reticulocytes" in MCE Product Catalog:
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6 Publications Verification
Synonyms: NSC168807
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PD146176 (NSC168807), a 15-Lipoxygenase (15-LO) inhibitor, inhibits rabbit reticulocyte 15-LO (Ki=197 nM, IC50=0.54 μM). PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice .
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2 Cited Publications
Cat. No.: HY-D0150
CAS No.: 107091-89-4
Cat. No.: HY-D0996
CAS No.: 181885-68-7
Cat. No.: HY-167846
CAS No.: 2417685-83-5
YLIU-4-105-1 is a Type II JAK2 inhibitor. YLIU-4-105-1 binds to the ATP-binding pocket of JH1. YLIU-4-105-1 has in vivo pharmacodynamic activity as evidenced by inhibiting pSTAT5, reducing spleen to body weight, and lowering blood reticulocyte counts in a dose-dependent manner .
Cat. No.: HY-P3756
CAS No.: 180088-82-8
Synonyms: EMP-1
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L-(+)-threo-Chloramphenicol ((+)-Chloramphenicol) is the S,S-stereoisomer of Chloramphenicol (HY-B0239). L-(+)-Threo-chloramphenicol inhibits protein synthesis in reticulocytes. L-(+)-threo-Chloramphenicol also inhibits the oxidative activity of isolated mitochondria .
Cat. No.: HY-123341
CAS No.: 54232-59-6
Synonyms: 9-KODE
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9-OxoODE results from oxidation of the allylic hydroxyl of either 9(S)- or 9(R)-HODE. Rabbit reticulocyte plasma and mitochondrial membranes contain both 9- and 13-oxoODEs, representing about 2% of the total linoleate residues in the membranes. Most of these oxidized linoleate residues are esterified to membrane lipids.
Cat. No.: HY-174495
Human EPO mRNA encodes the human erythropoietin (EPO) protein, a hormone that controls erythropoiesis, or red blood cell production. EPO also plays a role in wound healing and the brain’s response to neural injury. Kariko et al. showed that transfection of EPO mRNA in vivo resulted in significant increases of both reticulocyte counts and hematocrits.
Cat. No.: HY-N13880
CAS No.: 69579-74-4
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Cat. No.: HY-W995025
CAS No.: 24397-89-5
Synonyms: (+)-Actinobolin
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Actinobolin ((+)-Actinobolin) is an antibiotic, that inhibits protein synthesis by targeting bacterial and eukaryotic ribosomes. Actinobolin inhibits Mycobacterium smegmatis, Escherichia coli and rabbit reticulocyte lysate (RRL) with an IC50 of 19.2, 27.9, and 288 μmol/L, respectively .
Cat. No.: HY-W995025A
CAS No.: 18802-17-0
Synonyms: (+)-Actinobolin hemisulfate
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Actinobolin hemisulfate ((+)-Actinobolin hemisulfate) is the hemisulfate form of Actinobolin (HY-W995025). Actinobolin hemisulfate is an antibiotic, that inhibits protein synthesis by targeting bacterial and eukaryotic ribosomes. Actinobolin hemisulfate inhibits Mycobacterium smegmatis, Escherichia coli and rabbit reticulocyte lysate (RRL) with an IC50 of 19.2, 27.9, and 288 μmol/L, respectively .
Cat. No.: HY-170831
CAS No.: 2757191-62-9
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DS79932728 is an orally active inhibitor for G9a and GLP with IC50 of 12.6 nM and 75.7 nM. DS79932728 induces the production of γ-globin, thereby increasing the level of fetal hemoglobin (HbF). DS79932728 increases F-reticulocytes (F-rets) proportion and exhibits good oral absorption characteristics in cynomolgus monkey models .
Cat. No.: HY-W747575
CAS No.: 167354-91-8
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(±)13-HODE cholesteryl ester is originally extracted from atherosclerotic lesions1 and shown to be produced by Cu2+-catalyzed oxidation of LDL. Later studies determined that 15-LO from rabbit reticulocytes and human monocytes were able to metabolize cholesteryl linoleate, a major component of LDL, to 13-HODE cholesteryl ester.
Cat. No.: HY-123016A
CAS No.: 33783-76-5
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(±)9-HODE cholesteryl ester is originally extracted from atherosclerotic lesions1 and shown to be produced by Cu2+-catalyzed oxidation of LDL.2 Later studies determined that 15-LO from rabbit reticulocytes and human monocytes were able to metabolize cholesteryl linoleate, a major component of LDL, to 9-HODE cholesteryl ester.
Cat. No.: HY-119894
CAS No.: 12656-40-5
Synonyms: NSC 102809
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Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active against Gram-positive bacteria, including S. aureus, S. epidermidis, and S. pyogenes (MICs=25, 25, and 3.1 μg/mL, respectively).2 Althiomycin inhibits protein synthesis in E. coli when used at concentrations of 1 and 10 μg/mL but not in isolated rabbit reticulocytes at 100 μg/mL.
Cat. No.: HY-103157R
CAS No.: 4079-26-9
Synonyms: NSC168807 (Standard)
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PD146176 (Standard) is the analytical standard of PD146176. This product is intended for research and analytical applications. PD146176 (NSC168807), a 15-Lipoxygenase (15-LO) inhibitor, inhibits rabbit reticulocyte 15-LO (Ki=197 nM, IC50=0.54 μM). PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice .
Cat. No.: HY-D0150A
CAS No.: 2394903-71-8
Cat. No.: HY-DY2021
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Reticulocyte Staining Solution is a vital staining solution that can be used for vital staining of reticulocytes.
Cat. No.: HY-P3756A
Synonyms: EMP-1 acetate
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Cat. No.: HY-129795
CAS No.: 119433-80-6
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Thiazolylalanine is a synthetic non-protein amino acid containing a thiazole heterocycle. Thiazolylalanine exhibits dual activities of stimulating protein synthesis and inducing protein degradation in rat reticulocytes, but exerts no effects on protein metabolism or the thermolability of phosphoenolpyruvate carboxykinase in hepatoma cells. Thiazolylalanine can serve as the N-terminal component of tripeptide ligands for the synthesis of various organometallic complexes such as gold, mercury, CyRu (II) Cl2, and Cp*Rh (III) Cl2. Thiazolylalanine finds wide application in the research of breast cancer and other related diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
