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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
350 Results for "
SUMO
" in MedChemExpress (MCE) Product Catalog:
Products (350)
350 Results for "SUMO" in MCE Product Catalog:
40
40 Publications Verification
Synonyms: TAK-981
Target:
Research Areas:
Subasumstat (TAK-981) is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities .
39
39 Cited Publications
Target:
Research Areas:
ML-792 is a potent and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50 values of 3 and 11 nM, respectively) compared with NAE/NEDD8 and UAE/ubiquitin (IC50> values of 32 μM and >100 μM, respectively) .
17
Category:
Plants Monophenols Ginkgoaceae Extract Simple Phenylpropanols Ketones, Aldehydes, Acids Phenols Ginkgo biloba L. Phenylpropanoids Disease Research Fields Cancer
Target:
12
12 Cited Publications
Target:
Research Areas:
2-D08 is a cell permeable, mechanistically unique inhibitor of protein SUMOylation. 2-D08 also inhibits Axl with an IC50 of 0.49 nM.
7
7 Cited Publications
Cat. No.: HY-N2360
CAS No.: 19202-36-9
Category:
Flavonoids Phenols Polyphenols Plants Disease Research Fields Selaginella tamariscina (P. Beauv.) Spring Biflavones Cancer Selaginellaceae Extract
Target:
5
5 Cited Publications
Cat. No.: HY-N0330
CAS No.: 96990-18-0
4
4 Cited Publications
Target:
Research Areas:
N106 is a first-in-class sarcoplasmic reticulum calcium ATPase (SERCA2a) SUMOylation activator. N106 directly activates the SUMO-activating enzyme, E1 ligase. N106 can be used for heart failure research .
4
4 Cited Publications
Cat. No.: HY-P70700A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: STING1; HSTING; Prev. TMEM173; N-Terminal Methionine-Proline-Tyrosine-Serine Plasma Membrane Tetraspanner; Transmembrane Protein 173; Stimulator Of Interferon Response CGAMP Interactor-DeltaC; STING; Stimulator Of Interferon Response CGAMP Interactor-Delt
Species:
Human
Source:
E. coli
4
4 Cited Publications
Cat. No.: HY-P72238
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSP90AA1; Heat Shock 86 KDa; Prev. HSPC1; FLJ31884; Prev. HSPCA; HSP90A; Prev. HSPCAL4; HSP 86; HSP90N; HSP86; Hsp89; LAP-2; Hsp90; Heat Shock Protein 90kDa Alpha Family Class A Member 1; Heat Shock Protein 90kDa Alpha (Cytosolic), Class A Member 1; Heat
Species:
Human
Source:
E. coli
3
Research Areas:
Vialinin A (Terrestrin A) is a p-terphenyl compound that can be derived from a Chinese edible mushroom. Vialinin A is an inhibitor of ubiquitin-specific peptidase 4 (USP4) and has anti-inflammatory and antioxidant properties. Vialinin A can alleviate cerebral ischaemia-reperfusion injury-induced neurological deficits and neuronal apoptosis. Vialinin A promotes activation of Keap1-Nrf2-ARE signaling pathway and increases the protein degradation of Keap1. Vialinin A possesses various pharmacological activities in cancer, Kawasaki disease, asthma, and pathological scarring. Vialinin A is a potent inhibitor of TNF-α, USP4, USP5, and sentrin/SUMO-specific protease 1 (SENP1). Vialinin A can be studied in reseach for autoimmune diseases, cancer and ischaemic stroke .
2
2 Cited Publications
Target:
Research Areas:
COH000 is an allosteric, covalent and irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme) (E1), with an IC50 of 0.2 μM for SUMOylation in vitro .
2
2 Cited Publications
Cat. No.: HY-P80351
Synonyms: DAP1 antibody;
GAP modifying protein 1 antibody;
GMP 1 antibody;
OFC10 antibody;
PIC 1 antibody;
PIC1 antibody;
SENP2 antibody;
Sentrin 1 antibody;
Sentrin antibody;
Small ubiquitin related modifier 1 antibody;
Small ubiquitin-like modifier 1 antibody;
Small ubiquitin-related modifier 1 antibody;
SMT3 antibody;
SMT3 homolog 3 antibody;
SMT3 suppressor of mif two 3 homolog 1 antibody;
SMT3, yeast, homolog 3 antibody;
Smt3C antibody;
SMT3H3 antibody;
SUMO-1 antibody;
SUMO1 antibody;
SUMO1_HUMAN antibody;
Ubiquitin homology domain protein PIC1 antibody;
Ubiquitin Like 1 antibody;
Ubiquitin like protein SMT3C antibody;
Ubiquitin like protein UBL1 antibody;
Ubiquitin-homology domain protein PIC1 antibody;
Ubiquitin-like protein SMT3C antibody;
Ubiquitin-like protein UBL1 antibody;
UBL 1 antibody;
UBL1 antibody
2
2 Cited Publications
Cat. No.: HY-P70700
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: STING1; HSTING; Prev. TMEM173; N-Terminal Methionine-Proline-Tyrosine-Serine Plasma Membrane Tetraspanner; Transmembrane Protein 173; Stimulator Of Interferon Response CGAMP Interactor-DeltaC; STING; Stimulator Of Interferon Response CGAMP Interactor-Delt
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P72262
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HDAC1; GON-10; Prev. RPD3L1; Reduced Potassium Dependency, Yeast Homolog-Like 1; HD1; Protein Decrotonylase HDAC1; Protein Deacetylase HDAC1; Histone Deacetylase; Protein Deacylase HDAC1; RPD3; Histone Deacetylase 1; KDAC1
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P702829
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KEAP1; Kelch-Like Protein 19; Kelch Like ECH Associated Protein 1; MGC10630; KLHL19; MGC20887; INrf2; MGC1114; Kelch-Like ECH-Associated Protein 1; MGC4407; KIAA0132; MGC9454; Kelch-Like Family Member 19; KEAP1 Delta C; Cytosolic Inhibitor Of Nrf2; INRF2
Species:
Mouse
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P71601Y
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1F10; MGC119832; Interleukin 1 Family Member 10; MGC119833; IL-1HY2; MGC11983; IL1-Theta; IL1HY2; IL-1F10; Interleukin-1 Receptor Antagonist-Like FIL1 Theta; FKSG75; Interleukin 1 Family, Member 10 (Theta); IL-38; Interleukin 1 Family Member 10 (Theta)
Species:
Mouse
Source:
E. coli
1
1
1
1 Cited Publications
Cat. No.: HY-P71288
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SENP2; Sentrin (SUMO1) Specific Peptidase 2; SUMO Specific Peptidase 2; Sentrin/SUMO-Specific Protease SENP2; KIAA1331; SMT3-Specific Isopeptidase 2; SMT3IP2; Sentrin-Specific Protease 2; AXAM2; DKFZp762A2316; SUMO1/Sentrin/SMT3 Specific Peptidase 2; Smt3
Species:
Human
Source:
E. coli
1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
