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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
SeP
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "SeP" in MCE Product Catalog:
11
11 Publications Verification
Synonyms: SeP-363856 hydrochloride; SeP-856 hydrochloride
Target:
Research Areas:
SEP-363856 (SEP-856) hydrochloride, an orally active TAAR1 and 5-HT1A agonist and CNS active psychotropic agent with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects. SEP-363856 hydrochloride has the potential for the study of schizophrenia .
Synonyms: SeP-225289 hydrochloride
Research Areas:
Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively.
Cat. No.: HY-W027382
CAS No.: 67268-37-5
Target:
Research Areas:
SEP-227900 is an orally active and potent DAAO (DAO) inhibitor with potential inhibitory applications. The biological activity of SEP-227900 may show benefits in diseases associated with vitamin D or sunlight exposure. SEP-227900 is expected to play an important role in improving cancer prognosis .
Cat. No.: HY-136109A
CAS No.: 1310426-33-5
Synonyms: SeP-363856; SeP-856
Target:
Research Areas:
SEP-363856 (SEP-856), an orally active TAAR1 and 5-HT1A agonist and CNS active psychotropic agent with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects. SEP-363856 (SEP-856) has the potential for the study of schizophrenia .
Cat. No.: HY-136109B
CAS No.: 1310426-29-9
Synonyms: (Rac)-SeP-363856; (Rac)-SeP-856
Target:
Research Areas:
(Rac)-SEP-363856 is the racemate of SEP-363856. SEP-363856（SEP-856）, an orally active and CNS active psychotropic agent with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects. SEP-363856 （SEP-856） has the potential for the treatment of schizophrenia .
Cat. No.: HY-136109E
CAS No.: 2375116-27-9
Synonyms: SeP-856 mesylate
Target:
Research Areas:
SEP-363856 (SEP-856) mesylate, an orally active TAAR1 and 5-HT1A agonist and CNS active psychotropic agent with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects. SEP-363856 mesylate has the potential for the study of schizophrenia .
Cat. No.: HY-14545B
CAS No.: 2974362-88-2
Target:
Research Areas:
SEP4199 is an orally active 5-HT7 receptor ligand, with a Ki value of 66 nM for human 5-HT7R and 16 nM for human D2R. SEP4199 mediates antidepressant effects. SEP4199 is applicable for the research of bipolar depression .
Cat. No.: HY-120914
CAS No.: 170950-29-5
Synonyms: GO-Y015
Target:
Glutathione Peroxidase Keap1-Nrf2 Heme Oxygenase (HO) Reactive Oxygen Species (ROS) Apoptosis Mitochondrial Metabolism Drug Derivative TrxR
Research Areas:
TrxR1-IN-B19 (GO-Y015) is a Curcumin (HY-N0005) derivative and TrxR1 inhibitor. TrxR1-IN-B19 inhibits de novo selenoprotein synthesis, suppresses SeP and GPx expression, and impairs selenium incorporation into Sec-tRNA[Sec]. TrxR1-IN-B19 induces Nrf2 accumulation through Keap1 cysteine modification, HO-1 expression, GSH synthesis, ROS accumulation, ER stress, mitochondrial dysfunction, Apoptosis, and G2/M phase arrest. TrxR1-IN-B19 improves glucose tolerance and insulin sensitivity, lowers blood glucose, inhibits tumor growth, and reduces arsenic accumulation. TrxR1-IN-B19 can be used for research on type 2 diabetes, arsenite-induced toxicity, and gastric cancer .
Cat. No.: HY-U00199A
CAS No.: 151776-26-0
Synonyms: (S)-N-Desmethyl zopiclone; SeP-174559
Target:
Research Areas:
(S)-Norzopiclone ((S)-N-Desmethyl zopiclone; SEP-174559) is a metabolite of Zopiclone with anxiolytic and anticonvulsant effects. (S)-Norzopiclone has benzodiazepine-like actions at γ2-bearing subtypes of the GABAA receptor and inhibits nACh and NMDA receptors .
Cat. No.: HY-12850
CAS No.: 675126-05-3
Synonyms: SeP 225289
Research Areas:
Dasotraline is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively.
Cat. No.: HY-RS10752
Target:
Research Areas:
PLXNB1 Human Pre-designed siRNA Set A contains three designed siRNAs for PLXNB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12641
Target:
Research Areas:
SELENOP Human Pre-designed siRNA Set A contains three designed siRNAs for SELENOP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18273
Target:
Research Areas:
Ephx2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ephx2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08514
Target:
Research Areas:
MMEL1 Human Pre-designed siRNA Set A contains three designed siRNAs for MMEL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-136109H
CAS No.: 1310422-02-6
Synonyms: (Rac)-SeP-363856 hydrochloride; (Rac)-SeP-856 hydrochloride
Target:
Research Areas:
(Rac)-Ulotaront hydrochloride ((Rac)-SEP-363856 hydrochloride) is the racemate of Ulotaront hydrochloride (HY-136109). Ulotaront hydrochloride, an orally active and CNS active psychotropic agent with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects. Ulotaront has the potential for the treatment of schizophrenia .
Cat. No.: HY-P700428
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PLXNB1; Semaphorin Receptor SeP; Prev. PLXN5; PLEXIN-B1; SeP; Plexin-B1; KIAA0407; Plexin 5; Plexin B1; PLXNB1 Protein
Species:
Human
Source:
HEK293
Cat. No.: HY-P82179A
Synonyms: SeP15; 9430015P09Rik
Cat. No.: HY-RS18579
Target:
Research Areas:
Selenop Mouse Pre-designed siRNA Set A contains three designed siRNAs for Selenop gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
