5 Results for "

Sophoridine

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Sophoridine" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-N1373
CAS No.: 6882-68-4
Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .
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Cat. No.: HY-N1402
CAS No.: 54809-74-4
Synonyms: Sophoridine N-oxide
Oxysophoridine (Sophoridine N-oxide) is a bioactive alkaloid extracted from the Sophora alopecuroides Linn. Oxysophoridine (Sophoridine N-oxide) shows anti inflammatory, anti oxidative stress and anti apoptosis effects .
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Cat. No.: HY-N1373A
CAS No.: 83148-91-8
Synonyms: (+)-Sophoridine
d-Sophoridine ((+)-Sophoridine) is the dextro isoform of Sophoridine (HY-N1373), which is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .
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Cat. No.: HY-N1373R
CAS No.: 6882-68-4
Sophoridine (Standard) is the analytical standard of Sophoridine. This product is intended for research and analytical applications. Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity .
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Cat. No.: HY-155158
CAS No.: 2241283-11-2
Target:  

Ferroptosis

Research Areas:  

Cancer

Anticancer agent 147 (compound 6j) is a derivative of sophoridine (HY-N1373) and is a ferroptosis inducer. Anticancer agent 147 can promote the accumulation of intracellular Fe 2+, reactive oxygen species (ROS) and MDA, increase ER stress, and upregulate the expression of the activating transcription factor ATF3. Anticancer agent 147 has good anti-liver cancer effects in vitro and in vivo .
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