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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
TBPS
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "TBPS" in MCE Product Catalog:
Synonyms: Ro 16-6028
Target:
Research Areas:
Bretazenil (Ro 16-6028) is a partial agonist at the gamma-aminobutyric acid A (GABAA) receptor-linked benzodiazepine site. Bretazenil is potent benzodiazepine examined, exhibiting an IC50 (concentration at which half-maximal inhibition of specific [35S]TBPS binding occurs) of 6.1 nM. Bretazenil shows an EC50 of 10 nM for recombinant α1β1γ2. Anticonvulsant effects .
Cat. No.: HY-RS14266
Target:
Research Areas:
TBP Human Pre-designed siRNA Set A contains three designed siRNAs for TBP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18225
Target:
Research Areas:
Tbp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tbp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-105567A
CAS No.: 467-22-1
Target:
Research Areas:
Carbiphene hydrochloride is a GABAA receptor allosteric modulator. Carbiphene hydrochloride inhibits [ 35S] TBPS binding and enhances [ 3H] muscimol binding on rat forebrain membranes, acting on specific GABAA receptor subsets. Carbiphene hydrochloride can be used in research related to schizophrenia .
Cat. No.: HY-RS24702
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Research Areas:
Tbp Rat Pre-designed siRNA Set A contains three designed siRNAs for Tbp gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-189567
Research Areas:
TBP-EQ is a cationic aggregation-induced emission photosensitizer and luminogen that enables bright red aggregation-state fluorescence imaging. TBP-EQ generates reactive oxygen species (ROS) via Type I/II pathways under light irradiation. TBP-EQ undergoes light-triggered translocation from the plasma membrane to mitochondria, enhancing penetration and mitochondrial enrichment, and induces oxidative plasma membrane damage, increased permeability, as well as mitochondrial oxidative stress, dysfunction, and depolarization. TBP-EQ exhibits photodynamic cytotoxicity against breast cancer cells, and intratumoral injection followed by light activation inhibits tumor growth. TBP-EQ preferentially accumulates in breast cancer cells and prolongs tumor retention while reducing off-target fluorescence. TBP-EQ can be used for breast cancer-related research .
Cat. No.: HY-114811
CAS No.: 25006-32-0
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Research Areas:
Leptophos oxon, a metabolite of leptophos, is a GABAA receptor chloride channel inhibitor with an IC50 values of 89.6 μM. Leptophos oxon inhibits GABA-induced chloride influx, binds to GABAA receptor-associated TBPS sites, and inhibits TBPS binding to voltage-dependent chloride channels. Leptophos oxon is a insecticide. Leptophos oxon can be used for the research of neurological disease .
Cat. No.: HY-105567
CAS No.: 15687-16-8
Target:
Research Areas:
Carbiphene is a GABAA receptor allosteric modulator. Carbiphene inhibits [ 35S] TBPS binding and enhances [ 3H] muscimol binding on rat forebrain membranes, acting on specific GABAA receptor subsets. Carbiphene can be used in research related to schizophrenia .
Cat. No.: HY-105056R
CAS No.: 84379-13-5
Synonyms: Ro 16-6028 (Standard)
Target:
Research Areas:
Bretazenil (Standard) is the analytical standard of Bretazenil (HY-105056). This product is intended for research and analytical applications. Bretazenil (Ro 16-6028) is a partial agonist at the gamma-aminobutyric acid A (GABAA) receptor-linked benzodiazepine site. Bretazenil is potent benzodiazepine examined, exhibiting an IC50 (concentration at which half-maximal inhibition of specific [35S]TBPS binding occurs) of 6.1 nM. Bretazenil shows an EC50 of 10 nM for recombinant α1β1γ2. Anticonvulsant effects .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
