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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
TD 428
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "TD 428" in MCE Product Catalog:
Target:
Research Areas:
TD-428 is a BRD4/BET PROTAC degrader. TD-428 induces the degradation of BRD4 and BET proteins via the ubiquitin-proteasome pathway by recruiting cereblon, thereby inhibiting C-MYC transcription and cancer cell proliferation. TD-428 can be used in the research of metastatic castration-resistant prostate cancer and prostate cancer .
Cat. No.: HY-184562
CAS No.: 2324144-03-6
Research Areas:
TD-106-PEG3-aniline (Compound 17b) is an aminobenzotriazinyl glutarimide analog that binds to cereblon (CRBN). Equipped with a PEG3 linker and an aniline group, TD-106-PEG3-aniline serves as a E3 ligase ligand-Linker conjugates for the synthesis of PROTAC TD-428 (HY-114407) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
