2 Results for "

TMP269

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "TMP269" in MCE Product Catalog:

22
22 Cited Publications
Cat. No.: HY-18360
CAS No.: 1314890-29-3
Target:  

HDAC

Research Areas:  

Cancer

TMP269 is a novel and selective class IIa histone deacetylase (HDAC) inhibitor with IC50s of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.
loading...
    loading...
Cat. No.: HY-189948
Target:  

HDAC Drug Derivative

Research Areas:  

Inflammation/Immunology

HDAC4/HDAC7-IN-1 is a TMP269 (HY-18360)-derived HDAC4/HDAC7 selective inhibitor. HDAC4/HDAC7-IN-1 selectively inhibits HDAC7-dependent transcription relative to HDAC4-dependent transcription. HDAC4/HDAC7-IN-1 selectively disrupts the HDAC7-Aiolos protein interaction but does not interfere with the HDAC4-JunB complex.=HDAC4/HDAC7-IN-1 can be used for research on HDAC4/HDAC7-mediated related diseases, such as inflammatory diseases .
loading...
    loading...