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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
TXA707
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "TXA707" in MCE Product Catalog:
Cat. No.: HY-153695
CAS No.: 1609670-89-4
TXA707 is an FtsZ-targeting antibacterial agent. TXA707 disrupts bacterial septum formation, induces cell enlargement, causes penicillin-binding protein mislocalization, and triggers cell lysis in Staphylococcus aureus cells. TXA707 can be used for the research of Staphylococcus aureus infections .
Cat. No.: HY-150699
CAS No.: 1459695-66-9
TXA6101 is a bacterial protein FtsZ (filamentous temperature-sensitive protein Z) inhibitor that inhibits bacterial division. TXA6101 has antimicrobial activity against MRSA isolates expressing either the G193D or G196S mutant FtsZ with the MIC value of 1 μg/mL, retains significant activity against the TXA707-resistant FtsZ mutant. TXA6101 can be used as a potential method against Gram-negative bacterial infections .
Cat. No.: HY-187955
CAS No.: 1609670-80-5
TXA709 is an orally active FtsZ-targeting prodrug that hydrolyzes to the active metabolite TXA707 (HY-153695). TXA709 inhibits bacterial (bacterial) Z-ring cytokinesis by targeting FtsZ, exerts bactericidal activity against Staphylococcus aureus isolates including Vancomycin (HY-B0671)-, Daptomycin (HY-B0108)-, and Linezolid (HY-10394)-resistant strains, and shows synergistic effects when combined with Cefdinir (HY-B0136) or Oxacillin (HY-B0925A). TXA709 can be used for research on MRSA infections and Staphylococcus aureus infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
