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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Tfh cells
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Tfh cells" in MCE Product Catalog:
Cat. No.: HY-163480
CAS No.: 2796997-12-9
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Cat. No.: HY-148631
CAS No.: 2728727-91-9
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GSK137 is an orally active BCL6 inhibitor. GSK137 competitively blocks the protein-protein interactions of BCL6 with the corepressors SMRT, NCOR1, and BCOR. GSK137 produces only weak cell cycle arrest in multiple BCL6-positive diffuse large B-cell lymphoma cell lines and has almost no effect on tumor cell viability. GSK137 inhibits the generation of mouse germinal center B cells and Tfh cells, and downregulates TNP-specific IgM and IgG antibody levels. GSK137 can be used for research related to diffuse large B-cell lymphoma .
Cat. No.: HY-P991477
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Cat. No.: HY-P9S0062
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Rosnilimab (Mouse IgG2a) is a mouse-derived IgG2a antibody, Rosnilimab. Rosnilimab is a PD-1 agonistic monoclonal antibody. Rosnilimab (Mouse IgG2a) optimizes the inhibitory PD-1 signaling pathway without blocking PD-L1 binding; it also activates moderately activated PD-1 + T cells and eliminates PD-1 high cells, Tfh/Tph cells and Teff cells. Rosnilimab (Mouse IgG2a) reduces the secretion and gene expression of IFN-γ, CXCL13, IL-6 and TNF, decreases macrophage infiltration, and downregulates the gene expression of inflammatory myeloid cells. Rosnilimab (Mouse IgG2a) can be used in studies related to ulcerative colitis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
