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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
Thermodynamic
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "Thermodynamic" in MCE Product Catalog:
Category:
Ketones, Aldehydes, Acids Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-W013851
CAS No.: 150-39-0
Cat. No.: HY-115853
CAS No.: 78668-34-5
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Pyclen forms kinetically and thermodynamically stable nine-coordinate Ln (III) complexes, as well as Mn (II)-based MRI contrast agents. Pyclen-Based Mn(II) Complexes can be used for liver-specific MRI .
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1,5-Naphthalenedisulfonic acid (Armstrong's acid) is an aromatic disulfonic acid compound commonly used as an intermediate in the dye industry and organic synthesis. 1,5-Naphthalenedisulfonic acid is a pharmaceutical co-former that significantly improves the solubility and thermodynamic stability of poorly soluble drugs. 1,5-Naphthalenedisulfonic acid constructs a stable supramolecular network through coordination, hydrogen bonding, and electrostatic interactions, thereby effectively preventing drug crystallization. 1,5-Naphthalenedisulfonic acid exhibits certain cytotoxicity and antitumor activity in some human hepatoma cells. 1,5-Naphthalenedisulfonic acid can be used for research on human hepatoma .
Cat. No.: HY-W009071
CAS No.: 211366-30-2
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1,5-Naphthalenedisulfonic acid tetrahydrate is an aromatic disulfonic acid compound commonly used as an intermediate in the dye industry and organic synthesis. 1,5-Naphthalenedisulfonic acid tetrahydrate is a pharmaceutical co-former that significantly improves the solubility and thermodynamic stability of poorly soluble drugs. 1,5-Naphthalenedisulfonic acid tetrahydrate constructs a stable supramolecular network through coordination, hydrogen bonding, and electrostatic interactions, thereby effectively preventing drug crystallization. 1,5-Naphthalenedisulfonic acid tetrahydrate exhibits certain cytotoxicity and antitumor activity in some human hepatoma cells. 1,5-Naphthalenedisulfonic acid tetrahydrate can be used for research on human hepatoma .
Cat. No.: HY-115853A
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Pyclen dihydrochloride forms kinetically and thermodynamically stable nine-coordinate Ln (III) complexes, as well as Mn (II)-based MRI contrast agents. Pyclen-Based Mn(II) Complexes can be used for liver-specific MRI .
Cat. No.: HY-174800
CAS No.: 2230854-98-3
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ARN21929 is a Topoisomerase II inhibitor with an IC50 of 4.5 μM. ARN21929 exhibits excellent kinetic and thermodynamic solubility as well as metabolic stability. However, ARN21929 shows poor antiproliferative activity against A549, DU145, MCF7, HeLa, and A375 cells. ARN21929 can be used in the study of cancer .
Cat. No.: HY-153805
CAS No.: 1373391-77-5
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Z-NCTS is a small molecule that binds to mismatched RNA, recognizes the 5'-r (XGG)-3'/5'-r (XGG)-3' sequence, and acts as an RNA molecular glue. Z-NCTS induces the formation of tertiary structures in ribozymes and activates their RNA cleavage activity. As an RNA molecular glue, Z-NCTS enables small molecule-based strategies for regulating RNA structure and function. Z-NCTS binds to d (CGG)/d (CGG) double-stranded DNA, recognizes four guanine bases via hydrogen bonding, and stabilizes the double-stranded DNA. Z-NCTS binds to r (GGG)/r (GGG) double-stranded RNA and enhances the thermodynamic stability of the RNA duplex. Z-NCTS acts as a translation inhibitor by inducing the formation of stable hairpin structures in the 5'-UTR region of engineered mRNA, thereby blocking ribosomal access to the binding site .
Cat. No.: HY-115853B
CAS No.: 129135-03-1
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Pyclen sulfate forms kinetically and thermodynamically stable nine-coordinate Ln (III) complexes, as well as Mn (II)-based MRI contrast agents. Pyclen-Based Mn(II) Complexes can be used for liver-specific MRI .
Cat. No.: HY-187922
CAS No.: 1609170-61-7
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Rufutalkib is an orally active ALK modulator. It possesses thermodynamic and chemical stability, and can be used in research related to anaplastic large cell lymphoma, non-Hodgkin's lymphoma, inflammatory myofibroblastic tumor, neuroblastoma, glioblastoma, and ALK-positive malignancies .
Cat. No.: HY-187813
HDAC2-IN-4 is a HDAC2 inhibitor with an IC50 of 4.2 nM against human HDAC2. HDAC2-IN-4 binds to the active site of HDAC2 via hydrogen bonding and hydrophobic interactions, forming a thermodynamically stable and kinetically compatible protein-ligand complex to inhibit enzymatic activity. HDAC2-IN-4 inhibits cancer cell proliferation and exhibits low toxicity to normal cells. HDAC2-IN-4 can be used in studies related to human endocervical adenocarcinoma and Burkitt lymphoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
