2 Results for "

U251MG cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "U251MG cells" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-12833
CAS No.: 1313613-09-0
Purity:  99.76%
Target:  

Phosphatase Akt ERK

Research Areas:  

Others

AMZ30 is selective protein phosphatase methylesterase-1(PME-1) inhibitor with IC50s of 600 nM and 3.5 µM in human cell lysates and in HEK 293T cells, respectively. AMZ30 shows >100-fold selectivity relative to other serine hydrolases. AMZ30 reduces the demethylated form of PP2A in living cells. AMZ30 attenuates muscle cell differentiation. AMZ30 increases the resistance of U87MG and U251MG glioblastoma cells to t-BHP-induced oxidative stress. AMZ30can be used for the study of glioblastoma .
loading...
    loading...
Cat. No.: HY-160121
CAS No.: 76319-15-8
Synonyms: Patrinoside aglycone
Patrinoside aglucone (Compound 8) is an iridoid glucoside that can be isolated from the Valeriana tuberosa. Patrinoside aglucone has potent anticancer activity with G2/M phase tumor cell cycle arrest and apoptosis induction. Patrinoside aglucone also significantly inhibits the proliferation of cancer stem cells (such as MDA-MB-231 and U-251MG cells). Patrinoside aglucone has great anti-inflammatory activity by inhibiting NO release (IC50: 43.44 μM) and significantly reduces the level of TNF-α, IL-1β, IL-6, PGE2 and COX-2 .
loading...
    loading...