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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
UGM
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "UGM" in MCE Product Catalog:
Cat. No.: HY-113652
CAS No.: 1027102-49-3
UGM-IN-2 is a UGM inhibitor with a Kd of 20 μM. It binds to the UGM isoforms of K. pneumoniae (Klebsiella pneumoniae) and M. tuberculosis (Mycobacterium tuberculosis) and inhibits mycobacterial growth. UGM-IN-2 can be used in studies related to mycobacterial infections and tuberculosis .
Cat. No.: HY-180407
CAS No.: 1027102-50-6
UGM-IN-1 (compound 107) is a selective competitive inhibitor of Mycobacterium tuberculosis UDP-Galp mutase (UGM), encoded by Rv3809c. UGM-IN-1 inhibits the conversion of UDP-galactopyranose (UDP-Galp) to UDP-galactofuranose (UDP-Galf), thereby blocking the synthesis of key components of the mycobacterial cell wall, including mycolic acid-arabinogalactan (mAG) and liparabinomannan (LAM), leading to anti-mycobacterial activity against Mycobacterium tuberculosis. UGM-IN-1 is useful for research on tuberculosis, including drug-resistant tuberculosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
