1 Result for "

ZL-Pin13

" in MedChemExpress (MCE) Product Catalog:
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Cat. No.: HY-143903
CAS No.: 2883498-73-3
Target:  

PIN1 Bcl-2 Family c-Myc

Research Areas:  

Cancer

ZL-Pin13 is a covalent Pin1 inhibitor. ZL-Pin13 modifies Cys113, blocking Pin1-substrate interactions and peptidyl-prolyl cis/trans isomerase activity. ZL-Pin13 induces partial Pin1 degradation and downregulates MCL-1, cyclin D1, and c-Myc at both the protein and transcriptional levels. ZL-Pin13 can be used in research on triple-negative breast cancer .
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