Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
77 Results for "
acrylamide
" in MedChemExpress (MCE) Product Catalog:
Products (77)
77 Results for "acrylamide" in MCE Product Catalog:
35
35 Publications Verification
K-975 is a potent, selective and orally active TEAD inhibitor, with a strong inhibitory effect against protein-protein interactions between YAP1/TAZ and TEAD. K-975 covalently binds to Cys359 located in the palmitate-binding pocket of TEAD via an acrylamide structure. K-975 exhibits antitumor activity on malignant pleural mesothelioma .
2
2 Cited Publications
Synonyms: Bisacrylamide; MBA; Methylenebisacrylamide; N,N-Methylenebisacrylamide
1
1 Cited Publications
Target:
Research Areas:
BPK-25, an active acrylamide, promotes degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins by a post-translational mechanism involving covalent protein engagement. BPK-25 inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP .
1
1
1 Cited Publications
Synonyms: Oxiranecarboxamide; 2,3-Epoxypropanamide
Target:
Research Areas:
Glycidamide is the genotoxic metabolite of Acrylamide. Glycidamide can react with proteins, such as hemoglobin, or with DNA, and induces genotoxic effects .
1
1 Cited Publications
Target:
Research Areas:
BPK-21, an active acrylamide, suppresses T cell activation through blockade of ERCC3 function. BPK-21 specifically targets C342 in the helicase ERCC3 .
1
1 Cited Publications
DB008 is potent and selective PARP16 inhibitor with an IC50 value of 0.27 μM, containing an acrylamide electrophilic reagent. DB008 is membrane-permeable and marks PARP16 selectively . DB008 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
1
1 Cited Publications
Cat. No.: HY-155938
CAS No.: 2801702-34-9
Target:
Research Areas:
Cyano-myracrylamide is a broad-spectrum S-acyltransferase/zDHHC inhibitor with an IC50 of 1.35 μM against human zDHHC20. Cyano-myracrylamide covalently binds to DHHC family proteins through its cyanomethyl and acrylamide warheads, thereby blocking the lipid transfer processes such as palmitoylation of their substrate proteins (CD36, GobX, Myd88, Ras, and EGFR). Cyano-myracrylamide can be used in research on type 2 diabetes, lymphoma, and antiphospholipid syndrome .
Cat. No.: HY-P4070
CAS No.: 1188379-43-2
Target:
Research Areas:
Cat. No.: HY-29035
CAS No.: 201610-44-8
Dopamine acrylamide, a polyphenol derivative, can cross-link collagen mainly via noncovalent bonding under acidic-non-oxidized conditions .
Cat. No.: HY-D1871
CAS No.: 1838643-41-6
Cat. No.: HY-W095198
CAS No.: 7646-67-5
Cat. No.: HY-W115727C
CAS No.: 9003-05-8
Synonyms: acrylamide polymer,Nonionic,Mw 5-6 million
Cat. No.: HY-W098021
CAS No.: 24650-42-8
Synonyms: Photoinitiator-651
Target:
Research Areas:
2,2-Dimethoxy-2-phenylacetophenone is a hydrophobic benzoin ether-based free radical photoinitiator. 2,2-Dimethoxy-2-phenylacetophenone undergoes α-cleavage upon UV irradiation to generate benzoyl and substituted benzyl free radicals, thereby initiating photopolymerization reactions. 2,2-Dimethoxy-2-phenylacetophenone serves as a hydrophobic free radical photoinitiator for the photopolymerization of acrylamide and trimethylolpropane triacrylate in specific systems .
Cat. No.: HY-W872575
CAS No.: 1914971-04-2
Target:
Research Areas:
TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
Cat. No.: HY-155880
CAS No.: 80506-64-5
Synonyms: mPEG350-NH2
Target:
Research Areas:
mPEG350-amine (mPEG350-NH2) is a PEG-based amine that serves as a precursor for the synthesis of PEG acrylamide macromonomers. mPEG350-amine is used for the synthesis of polymeric micelles for drug delivery .
Cat. No.: HY-156392
Target:
Research Areas:
TCO4-PEG7-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG7-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
Cat. No.: HY-W923132
CAS No.: 193419-86-2
Synonyms: Acryloyloxy fluorescein
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
