10045 Results for "

agent

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1385

Chloroquine phosphate

1385 Publications Verification

Cat. No.: HY-17589

CAS No.: 50-63-5

Target:

Parasite Autophagy SARS-CoV Toll-like Receptor (TLR) HIV Antibiotic

Research Areas:

Infection Inflammation/Immunology Cancer

Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC₅₀=1.13 μM) .

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1385

Chloroquine

1385 Publications Verification

Cat. No.: HY-17589A

CAS No.: 54-05-7

Target:

Parasite Autophagy SARS-CoV Toll-like Receptor (TLR) HIV Antibiotic

Research Areas:

Infection Inflammation/Immunology Cancer

Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC₅₀=1.13 μM) .

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1385

Chloroquine dihydrochloride

1385 Publications Verification

Cat. No.: HY-17589B

CAS No.: 3545-67-3

Target:

Parasite Autophagy SARS-CoV Toll-like Receptor (TLR) HIV Antibiotic

Research Areas:

Infection Inflammation/Immunology Cancer

Chloroquine dihydrochloride is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine dihydrochloride is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine dihydrochloride is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC₅₀=1.13 μM) .

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899

Cisplatin

899 Cited Publications

Cat. No.: HY-17394

CAS No.: 15663-27-1

Synonyms: cis-Platinum; CDDP; cis-Diaminodichloroplatinum

Target:

DNA Alkylator/Crosslinker Ferroptosis Autophagy Pyroptosis Lipoxygenase

Research Areas:

Cancer

Cisplatin (CDDP) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy .

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728

Doxorubicin hydrochloride

728 Cited Publications

Cat. No.: HY-15142

CAS No.: 25316-40-9

Purity: 99.90%

Synonyms: Hydroxydaunorubicin hydrochloride; ADR

Category:

Infection Quinones Microorganisms Anthraquinones Disease Research Fields

Target:

Topoisomerase ADC Payloads AMPK Autophagy Apoptosis HIV HBV Mitophagy Antibiotic Bacterial Fluorescent Dye

Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride; ADR), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC₅₀s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy .

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