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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
anthranilate synthase
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "anthranilate synthase" in MCE Product Catalog:
Cat. No.: HY-W142073
CAS No.: 17332-70-6
Synonyms: 7-Methyltryptophan
Target:
7-Methyl-DL-tryptophan (7-Methyltryptophan) is an anthranilate synthase inhibitor that inhibits tryptophan biosynthesis. 7-Methyl-DL-tryptophan is also a tryptophan analog. 7-Methyl-DL-tryptophan can cause growth inhibition in tobacco, whereas a feedback-insensitive anthranilate synthase confers resistance and can be used as a selective agent to recover transgenic tobacco plants expressing this enzyme .
Target:
Amino Acid Derivatives Toll-like Receptor (TLR) MyD88 NF-κB Interleukin Related TNF Receptor Bacterial
Research Areas:
5-Methyl-DL-tryptophan is an orally active amino acid derivative with anti-inflammatory signaling effects. 5-Methyl-DL-tryptophan inhibits TLR4/MyD88 signaling and NF-κB activation/phosphorylation, reduces IL-6/IL-1β/TNF-α, and decreases the p-p65/p65 ratio. 5-Methyl-DL-tryptophan inhibits anthranilate synthase (Ki = 13 μM). 5-Methyl-DL-tryptophan inhibits bacterial growth. 5-Methyl-DL-tryptophan can be used in research on ulcerative colitis .
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Protocols
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