55

Baloxavir

55 Publications Verification

Cat. No.: HY-109025A

CAS No.: 1985605-59-1

Purity: 99.68%

Synonyms: Baloxavir acid; S-033447

Target:

Influenza Virus

Research Areas:

Infection Cancer

Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

51

Ivermectin

51 Cited Publications

Cat. No.: HY-15310

CAS No.: 70288-86-7

Purity: 98.28%

Synonyms: MK-933; CD-5024; K-237

Category:

Microorganisms Macrolide Antibiotics Antibiotics Antiviral Anti-parasitic Disease Research Disease Research Fields Cancer

Target:

Environmental Pollutants Antibiotic Mitophagy Bacterial Parasite Autophagy Flavivirus HSV HIV SARS-CoV Dengue Virus

Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X₄ and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

38

OSS_128167

38 Cited Publications

Cat. No.: HY-107454

CAS No.: 887686-02-4

Purity: 98.63%

Target:

Sirtuin HBV

Research Areas:

Infection Metabolic Disease Inflammation/Immunology Cancer

OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC₅₀s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

36

Pyridostatin trihydrochloride

36 Cited Publications

Cat. No.: HY-15176C

CAS No.: 2517456-88-9

Synonyms: RR82 trihydrochloride

Target:

DNA/RNA Synthesis G-quadruplex Flavivirus Src Virus Protease

Research Areas:

Cancer

Pyridostatin (RR82) trihydrochloride is a G-quadruplex (G4) inducer/stabilizer with a K_d of 490 nM. Pyridostatin trihydrochloride also acts as an inhibitor of Zika virus (ZIKV) NS2B-NS3 protease, with an IC₅₀ of 11.0 μM. Pyridostatin trihydrochloride interacts with G-quadruplex structures, regulates the expression of SRC and SUB1, and induces replication- and transcription-dependent DNA damage, growth arrest, and genomic instability. Pyridostatin trihydrochloride exhibits antiproliferative and antiviral activities. Pyridostatin trihydrochloride can be used in studies related to breast cancer, cervical cancer, and Zika virus infection .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

36

Pyridostatin TFA

36 Cited Publications

Cat. No.: HY-15176B

CAS No.: 1472611-44-1

Purity: 99.54%

Synonyms: RR82 TFA

Target:

DNA/RNA Synthesis G-quadruplex Flavivirus Src Virus Protease

Research Areas:

Cancer

Pyridostatin (RR82) TFA is a G-quadruplex (G4) inducer/stabilizer with a K_d of 490 nM. Pyridostatin TFA also acts as an inhibitor of Zika virus (ZIKV) NS2B-NS3 protease, with an IC₅₀ of 11.0 μM. Pyridostatin TFA interacts with G-quadruplex structures, regulates the expression of SRC and SUB1, and induces replication- and transcription-dependent DNA damage, growth arrest, and genomic instability. Pyridostatin TFA exhibits antiproliferative and antiviral activities. Pyridostatin TFA can be used in studies related to breast cancer, cervical cancer, and Zika virus infection .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

33

Ganciclovir

33 Cited Publications

Cat. No.: HY-13637

CAS No.: 82410-32-0

Purity: 99.89%

Synonyms: BW 759; 2'-Nor-2'-deoxyguanosine

Target:

CMV HSV Antibiotic Nucleoside Antimetabolite/Analog

Research Areas:

Infection Cancer

Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC₅₀ of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

33

Ganciclovir sodium

33 Cited Publications

Cat. No.: HY-13637A

CAS No.: 107910-75-8

Purity: 99.92%

Synonyms: BW 759 sodium; 2'-Nor-2'-deoxyguanosine sodium

Target:

CMV HSV Antibiotic Nucleoside Antimetabolite/Analog

Research Areas:

Infection Cancer

Ganciclovir (BW 759) sodium, a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir sodium also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir sodium inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir sodium has an IC₅₀ of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

17

Cidofovir

17 Cited Publications

Cat. No.: HY-17438

CAS No.: 113852-37-2

Synonyms: GS 0504; HPMPC; (S)-HPMPC

Target:

CMV Apoptosis DNA/RNA Synthesis Orthopoxvirus

Research Areas:

Infection Cancer

Cidofovir (GS 0504) is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer . Cidofovir also has anti-orthopoxvirus and anti-variola activities .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

17

Cidofovir dihydrate

17 Cited Publications

Cat. No.: HY-17438A

CAS No.: 149394-66-1

Synonyms: GS 0504 dihydrate; HPMPC dihydrate; (S)-HPMPC dihydrate

Category:

Infection Natural Products Endogenous metabolite Disease Research Fields Cancer

Target:

CMV DNA/RNA Synthesis Orthopoxvirus Apoptosis Endogenous Metabolite

Cidofovir (GS 0504; HPMPC; (S)-HPMPC) dihydrate is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir dihydrate inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir dihydrate induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer . Cidofovir dihydrate also has anti-orthopoxvirus and anti-variola activities .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

11

LDC4297

11 Cited Publications

Cat. No.: HY-12653

CAS No.: 1453834-21-3

Purity: 98.14%

Target:

CDK HIV HSV

Research Areas:

Infection

LDC4297 is a selective inhibitor of CDK7 with an IC₅₀ value of 0.13 nM. LDC4297 inhibits human cytomegalovirus (HCMV) replication with an EC₅₀ value of 24.5 nM. LDC4297 shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC₅₀ value of 0.02-1.21 μM. LDC4297 can be used for the research of infection .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

11

LDC4297 hydrochloride

11 Cited Publications

Cat. No.: HY-12653A

CAS No.: 2319747-14-1

Purity: 98.23%

Target:

CDK HIV HSV

Research Areas:

Infection

LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC₅₀ value of 0.13 nM. LDC4297 hydrochloride inhibits human cytomegalovirus (HCMV) replication with an EC₅₀ value of 24.5 nM. LDC4297 hydrochloride shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC₅₀ values of 0.02-1.21 μM. LDC4297 hydrochloride can be used for the research of infection .

Compare

loading...

Please select quantity

August 31

Get Quote

View All Sizes

11

Angelicin

11 Cited Publications

Cat. No.: HY-N0763

CAS No.: 523-50-2

Synonyms: Isopsoralen

Category:

Coumarins 500 - Internal Server Error | MedChemExpress

country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Cart

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.

antiviral replication

Oops!