23 Results for "

arsenical

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "arsenical" in MCE Product Catalog:

4
ZCL278
ZCL278
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4 Cited Publications
Cat. No.: HY-13963
CAS No.: 587841-73-4
Purity:  98.49%
Target:  

Ras Dengue Virus VSV Arenavirus

Research Areas:  

Infection Neurological Disease Metabolic Disease Cancer

ZCL278 is a selective Cdc42 inhibitor with Kds of 6.4 μM in fluorescence titration and 11.4 μM in surface plasmon resonance (SPR) measurement. ZCL278 is able to disrupt the Cdc42-ITSN interaction as well as GTP/GDP binding. ZCL278 has inhibitory effects on various enveloped viruses, but is ineffective against non-enveloped viruses. ZCL278 can be used for the studies of arsenic neurotoxicity and HER2-positive gastric cancer (GC) .
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Dimercaprol
Dimercaprol
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1 Cited Publications
Cat. No.: HY-B1285
CAS No.: 59-52-9
Synonyms: 2,3-Dimercapto-1-propanol; Dithioglycerol
Target:  

HIV

Research Areas:  

Infection

Dimercaprol (2,3-Dimercapto-1-propanol) is an anti-heavy metal-poisoning agent, which exhibits anti-HIV activity. Dimercaprol can be used for the study for arsenic, mercury, gold, lead, antimony, and other toxic metal poisoning .
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Dimethoxycurcumin
Dimethoxycurcumin
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Cat. No.: HY-100977
CAS No.: 160096-59-3
Purity:  98.89%
Synonyms: DiMC; CHC 004; Di-O-methylcurcumin
Target:  

Androgen Receptor Reactive Oxygen Species (ROS) Apoptosis NF-κB CDK Fatty Acid Synthase (FASN) Acetyl-CoA Carboxylase PI3K Akt AMPK ERK JNK

Research Areas:  

Metabolic Disease Inflammation/Immunology Cancer

Dimethoxycurcumin (DiMC) is a curcuminoid compound found in Curcuma longa. Dimethoxycurcumin is also an orally active thioredoxin reductase inhibitor (IC50 = 5.4 μM) and androgen receptor antagonist. Dimethoxycurcumin inhibits thioredoxin reductase, leading to oxidized thioredoxin accumulation, ROS production, DNA damage, glutathione depletion, mitochondrial membrane potential decrease, ATP depletion, S phase arrest, and apoptosis. Dimethoxycurcumin inhibits NF-κB, NADPH oxidase subunits, ATP synthase subunits, CDK4, cyclin-D1, FASN, ACC, and the IRS2-PI3K-Akt pathway, while activating AMPK, ERK, and JNK. Dimethoxycurcumin can be used for research on cancer, arsenic-induced hepatotoxicity, and tuberculosis .
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Melarsomine dihydrochloride
Melarsomine dihydrochloride
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Cat. No.: HY-138502A
CAS No.: 89141-50-4
Target:  

Parasite

Research Areas:  

Infection

Melarsomine dihydrochloride is a trivalent arsenical compound used as an adulticide. Melarsomine dihydrochloride can be used for the reserach of canine heartworm disease and other helminth infections .
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Melarsoprol
Melarsoprol
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Cat. No.: HY-119594
CAS No.: 494-79-1
Purity:  98.0%
Target:  

Parasite Apoptosis

Research Areas:  

Infection Neurological Disease Inflammation/Immunology Cancer

Melarsoprol, a melaminophenylarsine-type trivalent organic arsenical, is an important agent for African trypanosomiasis. Melarsoprol inhibits the growth of lymphoid leukemic cell by inducing apoptosis. Melarsoprol crosses the blood-brain barrier .
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N-Biotinyl p-aminophenyl arsenic acid
N-Biotinyl p-aminophenyl arsenic acid
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Cat. No.: HY-W741573
CAS No.: 212391-23-6
Target:  

nAChR

Research Areas:  

Neurological Disease

N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent that can bind to both streptavidin and dithiols. N-Biotinyl p-aminophenyl arsenic acid decreases the Rbungarotoxin-binding sites in reduced Torpedo nicotinic receptors (IC50 is 10-300 nM), and protects the receptor from irreversible alkylation by bromoacetylcholine .
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Darinaparsin
Darinaparsin
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Cat. No.: HY-14943
CAS No.: 69819-86-9
Purity:  ≥98.0%
Synonyms: ZIO-101; S-Dimethylarsino-glutathione
Target:  

Apoptosis

Research Areas:  

Cancer

Darinaparsin (ZIO-101), an organic arsenical, is a mitochondrial-targeted agent. Darinaparsin induces apoptosis in ancer cells, and has anticancer effects .
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Melarsomine
Melarsomine
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Cat. No.: HY-138502
CAS No.: 128470-15-5
Target:  

Parasite

Research Areas:  

Infection

Melarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections .
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Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside
Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside
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Cat. No.: HY-113949
CAS No.: 4099-85-8
Purity:  ≥96.0%
Target:  

Drug Intermediate

Research Areas:  

Others

Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside is a furanose derivative. Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside serves as an important intermediate for the synthesis of compounds such as arsenic-containing ribosides .
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Sodium butane-1-sulfonate
Sodium butane-1-sulfonate
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Cat. No.: HY-W017224
CAS No.: 2386-54-1
Synonyms: Sodium 1-butanesulfonate
Sodium butane-1-sulfonate (Sodium 1-butanesulfonate) is an ion-pair reagent. Sodium butane-1-sulfonate is often used in combination with tetramethylammonium hydroxide, malonic acid, etc. in reversed-phase ion-pair chromatography, and can improve the separation efficiency of species of elements such as arsenic and selenium .
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Dimercaprol (Standard)
Dimercaprol (Standard)
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Cat. No.: HY-B1285R
CAS No.: 59-52-9
Synonyms: 2,3-Dimercapto-1-propanol (Standard); Dithioglycerol (Standard)
Target:  

Reference Standards HIV

Research Areas:  

Infection

Dimercaprol (Standard) is the analytical standard of Dimercaprol. This product is intended for research and analytical applications. Dimercaprol (2,3-Dimercapto-1-propanol) is an anti-heavy metal-poisoning agent, which exhibits anti-HIV activity. Dimercaprol can be used for the study for arsenic, mercury, gold, lead, antimony, and other toxic metal poisoning .
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TrxR1-IN-B19
TrxR1-IN-B19
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Cat. No.: HY-120914
CAS No.: 170950-29-5
Synonyms: GO-Y015
Target:  

Glutathione Peroxidase Keap1-Nrf2 Heme Oxygenase (HO) Reactive Oxygen Species (ROS) Apoptosis Mitochondrial Metabolism Drug Derivative TrxR

Research Areas:  

Metabolic Disease Cancer

TrxR1-IN-B19 (GO-Y015) is a Curcumin (HY-N0005) derivative and TrxR1 inhibitor. TrxR1-IN-B19 inhibits de novo selenoprotein synthesis, suppresses SeP and GPx expression, and impairs selenium incorporation into Sec-tRNA[Sec]. TrxR1-IN-B19 induces Nrf2 accumulation through Keap1 cysteine modification, HO-1 expression, GSH synthesis, ROS accumulation, ER stress, mitochondrial dysfunction, Apoptosis, and G2/M phase arrest. TrxR1-IN-B19 improves glucose tolerance and insulin sensitivity, lowers blood glucose, inhibits tumor growth, and reduces arsenic accumulation. TrxR1-IN-B19 can be used for research on type 2 diabetes, arsenite-induced toxicity, and gastric cancer .
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Triphenylarsine
Triphenylarsine
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Cat. No.: HY-Y0443
CAS No.: 603-32-7
Synonyms: Triphenyl arsenic
Triphenylarsine (Triphenyl arsenic) is a kind of biological materials or organic compounds that are widely used in life science research.
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Glycobiarsol
Glycobiarsol
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Cat. No.: HY-122461
CAS No.: 116-49-4
Target:  

Parasite

Research Areas:  

Infection

Glycobiarsol is an organic arsenical compound, which can be used as an amoebicidal agent. Glycobiarsol exhibits toxicity and side effects .
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BRD4 Inhibitor-17
BRD4 Inhibitor-17
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Cat. No.: HY-145909
CAS No.: 2835555-10-5
Target:  

Epigenetic Reader Domain

Research Areas:  

Cancer

BRD4 Inhibitor-17 (Compound 5i) is a potent inhibitor of BRD4 with an IC50 of 0.33 μM. BRD4 Inhibitor-17 plays crucial role in regulating transcription of inflammatory, proliferation and cell cycle genes. BRD4 Inhibitor-17 serves as potential antidotes for arsenicals .
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Black tea extract
Black tea extract
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Cat. No.: HY-N16399
Category:  

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