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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
263 Results for "
azide derivative
" in MedChemExpress (MCE) Product Catalog:
Products (263)
263 Results for "azide derivative" in MCE Product Catalog:
6
6 Publications Verification
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DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction . DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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5 Cited Publications
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NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment . NH-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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2 Cited Publications
Cat. No.: HY-W040124
CAS No.: 50428-03-0
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2
2 Cited Publications
Cat. No.: HY-W051612A
CAS No.: 73823-66-2
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DL-Propargylglycine sodium is a Glycine (HY-Y0966) derivative. DL-Propargylglycine sodium is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
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2 Cited Publications
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DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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2 Cited Publications
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TD52, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 has less p-EGFR inhibition and has potent anti-cancer activity . TD52 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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2 Cited Publications
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TD52 dihydrochloride, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 dihydrochloride mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 dihydrochloride indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 dihydrochloride has less p-EGFR inhibition and has potent anti-cancer activity . TD52 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
1
1 Cited Publications
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TAMRA-Azide-PEG-biotin is a dye derivative of TAMRA (HY-135640). TAMRA-Azide-PEG-biotin contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
1
1 Cited Publications
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(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1, with an IC50 of 10.4 nM. (+)-JQ1 PA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
1
1 Cited Publications
N-Acetylmuramic acid-azide (Compound 2) is a derivative of N-acetylaminoacetic acid (NAM) in bacterial peptidoglycan. Incorporated into bacterial peptidoglycan during biosynthesis .
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1 Cited Publications
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DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
1
Cat. No.: HY-W011210
CAS No.: 198561-07-8
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Cat. No.: HY-D1314
CAS No.: 1386385-76-7
Synonyms: 6-FAM azide
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TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-P10303
CAS No.: 2767993-86-0
Synonyms: Cyclo[RGDfK(azide)]
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Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] (Cyclo[RGDfK(Azide)]) is a derivative of Cyclo (-RGDfK) (HY-P0023). Cyclo[Arg-Gly-Asp-D-Phe-Lys (Azide)] is a click chemistry reagent containing an azide group. Cyclo[Arg-Gly-Asp-D-Phe-Lys (Azide)] enables functionalization of alginate via SPAAC bioconjugation. Alginate hydrogels functionalized with Cyclo[Arg-Gly-Asp-D-Phe-Lys (Azide)] significantly promote cell expansion while maintaining cell pluripotency .
Cat. No.: HY-W008395
CAS No.: 220497-98-3
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Lenalidomide-PEG1-azide is a cereblon (CRBN)-recruiting azide-functionalized Lenalidomide (HY-A0003) derivative with a PEG1 linker, serving as a building block for synthesis of soluble epoxide hydrolase (sEH) PROTACs [1].Lenalidomide-PEG1-azide lacks definitive identity or significant scientific classification in associated literature.
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6-FAM-PEG3-Azide is a PEG-modified azide-functionalized fluorescein derivative that is used for labeling oligonucleotides. 6-FAM-PEG3-Azide is also a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. When 6-FAM-PEG3-Azide is co-incubated with boron clusters in a non-covalent manner, it enhances the cellular uptake and membrane permeability of 6-FAM (HY-66021). 6-FAM-PEG3-azide is applicable for fluorescence bioconjugation and probe development-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
