45 Results for "

benzoquinone

" in MedChemExpress (MCE) Product Catalog:
Products (45)

45 Results for "benzoquinone" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-139093A
CAS No.: 1331891-93-0
Purity:  ≥99.0%
Synonyms: APAP-Cys TFA
Target:  

Drug Derivative

Research Areas:  

Others

Paracetamol-cysteine TFA (APAP-Cys TFA) is a cysteine adduct of Acetaminophen (HY-66005). It forms when Acetaminophen is oxidized to the reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI) .
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1
1 Cited Publications
Cat. No.: HY-113283
CAS No.: 451-13-8
Purity:  99.46%
Homogentisic acid is an orally active, blood-brain barrier-permeable amyloidogenic compound that functions as both an amyloid component and a pigment precursor. Accumulation of homogentisic acid downregulates tight junction proteins (such as claudin-5, occludin, ZO-1) and impairs blood-brain barrier integrity. Homogentisic acid and its oxidation product benzoquinone acetic acid not only induce the aggregation and fibrosis of multiple proteins (such as Aβ1-42, α-synuclein, SAA, Transthyretin (TTR), atrial natriuretic peptide), but also trigger oxidative stress, damage to the Wnt/β-catenin pathway, and neurotoxicity, leading to ochronosis pigment deposition and synaptic dysfunction. At specific concentrations, homogentisic acid exerts no cytotoxicity or genotoxicity on human peripheral blood lymphocytes, and even counteracts the genotoxicity induced by Irinotecan (HY-16562). Homogentisic acid serves as an important tool molecule for investigating the mechanisms of diseases including ochronosis, secondary amyloidosis, Alzheimer's disease, and colorectal cancer .
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1
1 Cited Publications
Cat. No.: HY-W017464
CAS No.: 50700-49-7
Synonyms: N-Acetyl-4-benzoquinone Imine
NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver .
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1
1 Cited Publications
Cat. No.: HY-B1106
CAS No.: 319-89-1
Synonyms: Tetrahydroxy-1,4-benzoquinone; Tetrahydroxybenzoquinone
Research Areas:  

Cancer

Tetrahydroxyquinone (Tetrahydroxy-1,4-benzoquinone), a primitive anticataract agent, is a redox active benzoquinone. Tetrahydroxyquinone can take part in a redox cycle with semiquinone radicals, leading to the formation of reactive oxygen species (ROS) .
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1
1 Cited Publications
Cat. No.: HY-W007865
CAS No.: 7368-78-7
Synonyms: 4-Bromoguaiacol
Target:  

Drug Intermediate

Research Areas:  

Others

4-Bromo-2-methoxyphenol (4-Bromoguaiacol) is a phenolic compound. 4-Bromo-2-methoxyphenol serves as a synthetic intermediate for the preparation of PT70. 4-Bromo-2-methoxyphenol acts as a precursor for generating masked ortho-benzoquinone (MOB) 6 .
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1
1 Cited Publications
Cat. No.: HY-B1106A
CAS No.: 1215458-51-7
Synonyms: Tetrahydroxy-1,4-benzoquinone monohydrate; Tetrahydroxybenzoquinone monohydrate
Research Areas:  

Cancer

Tetrahydroxyquinone monohydrate (Tetrahydroxy-1,4-benzoquinone monohydrate), a primitive anticataract agent, is a redox active benzoquinone. Tetrahydroxyquinone monohydrate can take part in a redox cycle with semiquinone radicals, leading to the formation of reactive oxygen species (ROS) .
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Cat. No.: HY-W010323
CAS No.: 615-94-1
Synonyms: DHBQ
Research Areas:  

Others

2,5-Dihydroxy-1,4-benzoquinone (DHBQ) is a redox-active quinone-based organic ligand with antibacterial activity that can be obtained from fungal metabolites. After 2,5-Dihydroxy-1,4-benzoquinone is incorporated into the Fe (dhbq) metal-organic framework, a two-electron redox process occurs, which helps improve the discharge capacity of Li +-ion battery cathodes. 2,5-Dihydroxy-1,4-benzoquinone can be used to construct conductive metal-organic frameworks suitable for Li +-ion battery cathodes .
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Cat. No.: HY-W015816
CAS No.: 527-61-7
Synonyms: 2,6-DMBQ
Target:  

Photosystem II

Research Areas:  

Others

2,6-Dimethylbenzoquinone (2,6-DMBQ) is a benzoquinone derivative. 2,6-Dimethylbenzoquinone promotes Photosystem II-mediated photoelectrochemical water oxidation via electron transfer between spinach chloroplast Photosystem II membranes and carbon paste electrodes, and accepts electrons from Photosystem II during oxygen evolution assays. 2,6-Dimethylbenzoquinone undergoes direct photolysis in aqueous solution under 365 nm conditions, producing 2,6-dimethylhydroquinone and 3-hydroxy-2,6-dimethylbenzoquinone .
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Cat. No.: HY-N1677
CAS No.: 530-55-2
2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, 4E-BP1, and AMPK, and attenuates mTORC1 activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H2O2 generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness .
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Cat. No.: HY-108296
CAS No.: 1043-21-6
Purity:  ≥95.0%
Synonyms: Catalin K
Pirenoxine (Catalin K) is an antioxidant with lens-protective activity. Pirenoxine inhibits lens sclerosis, prevents lipid peroxidation and suppresses lens protein opacification. Pirenoxine blocks benzoquinone acetic acid-induced cataract progression. Pirenoxine can be used in research related to presbyopia and cataracts .
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Cat. No.: HY-100074
CAS No.: 1988-11-0
Target:  

Drug Intermediate

Research Areas:  

Others

2,6-Diisopropyl-p-benzoquinone is a drug intermediate that can be used for the synthesis of Geldanamycin (HY-15230) .
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Cat. No.: HY-Y0278
CAS No.: 118-75-2
Synonyms: Tetrachloro-p-benzoquinone; TCBQ
Chloranil (Tetrachloro-p-benzoquinone), an orally active metabolite of pentachlorophenol and hexachlorobenzene, is a widely used fungicide. Chloranil can induce ROS production. Chloranil induces neutrophil extracellular traps through the ROS-JNK-NOX2 pathway. Chloranil induces ferroptosis and neuroinflammation. Chloranil induces apoptosis of mouse embryonic stem cells .
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Cat. No.: HY-W017187
CAS No.: 3602-55-9
2-tert-Butyl-1,4-benzoquinone is a food additive oxidant, an electrophilic metabolite of Butylated hydroxyanisole (HY-B1066), and an antibacterial agent. 2-tert-Butyl-1,4-benzoquinone reduces virulence factors, activates Nrf2, and induces S-arylation of its negative regulator Keap1. 2-tert-Butyl-1,4-benzoquinone induces HO-1. 2-tert-Butyl-1,4-benzoquinone exhibits quorum sensing inhibitory activity against Chromobacterium violaceum .
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Cat. No.: HY-116139
CAS No.: 141112-29-0
Purity:  98.79%
Synonyms: Merlin; RP-201772
Research Areas:  

Others

Isoxaflutole (Merlin) is the inhibitor for HPPD that blocks benzoquinone biosynthesis, and results in the bleaching of weeds. Isoxaflutole can be used as herbicide .
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Cat. No.: HY-N8213
CAS No.: 573-40-0
Rapanone is a natural benzoquinone. Rapanone exhibits a broad spectrum of biological actions, including anti-tumor, antioxidant, anti-inflammatory, antibacterial and antiparasitic. Rapanone also is a potent and selective human synovial PLA2 inhibitor, with an IC50 of 2.6 μM .
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Cat. No.: HY-W100491
CAS No.: 935-92-2
Target:  

Drug Derivative

Research Areas:  

Cancer

Trimethylbenzoquinone (Compound 5) is a methylated benzoquinone. Trimethylbenzoquinone exhibits moderate cytotoxicity against K562 cells, with its IC50 being 0.75 μM. Trimethylbenzoquinone is completely unable to cause inter-strand DNA cross-linking and cannot alkylate DNA guanines. Trimethylbenzoquinone can be used to study the relationship between the nitrogen heterocyclic group and DNA cross-linking .
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Cat. No.: HY-118075
CAS No.: 606-06-4
Coenzyme Q2 is a benzoquinone electron carrier in the mitochondrial electron transport chain and a p53-dependent apoptosis inducer. Coenzyme Q2 induces p53 phosphorylation at Ser15, promoting p53 accumulation and functional activation. Coenzyme Q2 induces ROS generation, caspase-3 activation, DNA fragmentation, phosphatidylserine externalization, mitochondrial permeability transition pore opening, and oxidative phosphorylation uncoupling. Coenzyme Q2 inhibits Complex I, Complex III, and Complex IV activities, disrupting electron transport and membrane potential generation. Coenzyme Q2 induces excessive mitochondrial proton leak in forebrain mitochondria. Coenzyme Q2 causes loss of righting reflex in mice, accompanied by slow-wave delta EEG activity and reversible loss of wakefulness. Coenzyme Q2 inhibits lipid peroxidation and scavenges superoxide radicals. Coenzyme Q2 is used in research on leukemia, myocardial ischemia-reperfusion injury, and mitochondrial encephalomyopathy .
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Cat. No.: HY-N9610
CAS No.: 1065-31-2
Synonyms: Ubiquinone 30
Coenzyme Q6 (Ubiquinone 30) is a redox-active benzoquinone lipid and mitochondrial electron carrier. Coenzyme Q6 can be used in research on MASLD, mitochondrial diseases, pneumococcal diseases, and steroid-resistant nephrotic syndrome with FSGS .
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Cat. No.: HY-W090317
CAS No.: 137-18-8
Synonyms: DMBQ; 2,5-Dimethyl-p-quinone; Phlorone
Target:  

Urease

Research Areas:  

Others

2,5-Dimethyl-1,4-benzoquinone is a jack bean urease (HY-P2767) inhibitor (IC50: 0.98 μM). 2,5-Dimethyl-1,4-benzoquinone can be used in the study of soil urease activity in agriculture .
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Cat. No.: HY-N11537
CAS No.: 144078-11-5
Target:  

Others

Research Areas:  

Others

2-Methoxy-6-pentadecyl-1,4-benzoquinone (1c) is a pentadecyl derivative that can be isolated from seed oils of different iris plants such as I. pseudacorus, I. missouriensis and I. sibirica .
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