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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
63 Results for "
bulk macroautophagy
" in MedChemExpress (MCE) Product Catalog:
Products (63)
63 Results for "bulk macroautophagy" in MCE Product Catalog:
18
18 Publications Verification
Target:
Research Areas:
AR7 is an atypical RARA/RARα (retinoic acid receptor, alpha) antagonist. AR7 specifically activates chaperone-mediated-autophagy (CMA) activity without affecting macroautophagy .
5
5 Cited Publications
Synonyms: D-(+)-Xylose; (+)-Xylose; Wood sugar
4
4 Cited Publications
CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. CA-5f increases LC3B-II (a marker to monitor autophagy) and SQSTM1 protein, and also increases ROS production. Anti-tumor activity .
1
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Research Areas:
Propoxycaine hydrochloride is a voltage-gated sodium channel inhibitor. Propoxycaine hydrochloride delays monophasic A spike action potential recovery. Propoxycaine hydrochloride increases bulk lateral, rotational, and annular lipid fluidity in neuronal membrane lipid bilayers, with greater inner monolayer fluidization, and induces membrane protein clustering. Propoxycaine hydrochloride can be used for the research of pain .
1
1 Cited Publications
Synonyms: D-(+)-Xylose (Standard); (+)-Xylose (Standard); Wood sugar (Standard)
Cat. No.: HY-W087904
CAS No.: 5989-81-1
Synonyms: α-D-Lactose hydrate
Category:
Category:
Metabolic Disease Endogenous metabolite Disease Research Fields Sweeteners Saccharides Food Research Monosaccharides
Target:
Category:
Human Gut Microbiota Metabolites Natural Products Metabolic Disease Microorganism Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-W150340
CAS No.: 5965-66-2
Target:
Research Areas:
β-Lactose is a disaccharide commonly found in milk and dairy products. It consists of two monosaccharides, glucose and galactose, linked by β-glycosidic bonds. β-Lactose has various applications in the food industry, especially as a sweetener and bulking agent. Furthermore, it can be used as a substrate for enzymes involved in lactose metabolism and as a model compound for studying carbohydrate-protein interactions.
Cat. No.: HY-W489121
CAS No.: 774192-20-0
YTK-105 is a p62/ZZ binding domain ligand and Autophagy enhancer. YTK-105 activates p62-dependent selective macroautophagy. YTK-105 serves as an autophagy-targeting ligand (ATL) for synthesizing AUTOTAC degraders .
Cat. No.: HY-W779019
CAS No.: 1262683-58-8
Synonyms: D-(+)-Xylose-13C5; (+)-Xylose-13C5; Wood sugar-13C5
Cat. No.: HY-121095
CAS No.: 1591932-50-1
Target:
Research Areas:
Bizine, a Phenelzine analogue, is a potent and selective LSD1 inhibitor, with a b>Ki of 59 nM. Bizine can modulate bulk histone methylation in cancer cells. Bizine shows neuroprotective effects .
Cat. No.: HY-161742
CAS No.: 2410081-58-0
Fumagilin-105 is an autophagy-targeting chimera (AUTOTAC) that degrades MetAP2 via p62-mediated macroautophagy in a ubiquitination-independent manner. Fumagilin-105 can inhibit the migration of tumor cells and induce programmed cell death. Fumagilin-105 has anti-tumor activity. (p62-ZZ ligand (HY-W489121); target-binding ligand (HY-B0751); linker (HY-W245803)) .
Cat. No.: HY-W017508
CAS No.: 629-41-4
Cat. No.: HY-N0537S3
CAS No.: 131771-69-2
Synonyms: D-(+)-Xylose-2-13C; (+)-Xylose-2-13C; Wood sugar-2-13C
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
