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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
47 Results for "
caspase-7
" in MedChemExpress (MCE) Product Catalog:
Products (47)
47 Results for "caspase-7" in MCE Product Catalog:
123
123 Publications Verification
Synonyms: QVD-OPH; Quinoline-Val-Asp-Difluorophenoxymethylketone
Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC50 of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12. Q-VD-OPh can inhibits HIV infection. Q-VD-OPh is able to cross the blood-brain barrier.
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47
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45
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5 Cited Publications
Cat. No.: HY-P1003
CAS No.: 169332-61-0
Target:
Research Areas:
1
1 Cited Publications
Research Areas:
MMPSI is a potent and selective small molecule caspase 3 and caspase 7 inhibitor with an IC50 of 1.7 μM for human caspase-3. MMPSI can significantly reduce ischemia-reperfusion-induced infarct size in the isolated rabbit heart, and reduce apoptosis in both the ischemic myocardium and isolated cardiomyocytes. MMPSI can be used for researching cardioprotection .
Cat. No.: HY-N7368
CAS No.: 55366-56-8
Category:
Flavonols Plant Flavonoids Neurological Disease Phenols Polyphenols Other Families Extract Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-N6017
CAS No.: 19906-72-0
Cat. No.: HY-P991669
Synonyms: AML-01
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N-alpha-Tosyl-Lys chloromethyl ketone hydrochloride (TLCK hydrochloride) is a Serine protease inhibitor with an IC50 of 12.0 μM against Caspase-3, 54.5 μM against Caspase-6, and 19.3 μM against Caspase-7. It inhibits thrombin-induced nuclear translocation of FOXO1. N-alpha-Tosyl-Lys chloromethyl ketone hydrochloride can be used in research related to leukemia and cardiovascular diseases .
Cat. No.: HY-156096
CAS No.: 3033039-28-7
Research Areas:
HDAC3-IN-2 (compound 4i) is a pyrazinyl hydrazide-based HDAC3 inhibitor (IC50: 14 nM) that efficiently targets triple-negative breast cancer cells. HDAC3-IN-2 is cytotoxic with an IC50 of 0.55 μM against 4T1 and an IC50 of 0.74 μM against MDA-MB-231. HDAC3-IN-2 has anti-tumor efficacy in vivo in tumor-bearing mouse models, selectively increasing the acetylation levels of H3K9, H3K27 and H4K12, increasing the contents of apoptosis-related caspase-3, caspase-7 and cytochrome c, and reducing Proliferation-related Bcl-2, CD44, EGFR, and Ki-67 levels .
Cat. No.: HY-108312A
Purity: 98.7%
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Research Areas:
Cat. No.: HY-W033813
CAS No.: 1110670-49-9
Caspase-3/7 inhibitor I is a potent and reversible inhibitor of caspase-3 and caspase-7, with Kis of 60 and 170 nM, respectively. Caspase-3/7 inhibitor I can inhibit apoptosis in Camptothecin (HY-16560)-treated Jurkat cells and in chondrocytes .
Cat. No.: HY-108312
CAS No.: 319494-39-8
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Ac-VEID-CHO is a peptide-derived caspase inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC50 values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. Ac-VEID-CHO also inhibits VEIDase activity an IC50 value of 0.49 µM. Ac-VEID-CHO can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease .
Cat. No.: HY-P3476
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Research Areas:
Cat. No.: HY-12305G
CAS No.: 1135695-98-5
Cat. No.: HY-P74347
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CASP7; ICE-Like Apoptotic Protease 3; caspase 7; caspase-7; ICE-LAP3; CASP-7; CMH-1; Apoptotic Protease MCH-3; MCH3; Apoptotic Protease Mch-3; caspase 7, Apoptosis-Related Cysteine Peptidase; LICE2; caspase 7, Apoptosis-Related Cysteine Protease
Species:
Human
Source:
E. coli
Cat. No.: HY-P3234
CAS No.: 191338-87-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
