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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
230 Results for "
charge recombination
" in MedChemExpress (MCE) Product Catalog:
Products (230)
230 Results for "charge recombination" in MCE Product Catalog:
93
93 Publications Verification
Cat. No.: HY-D0041
CAS No.: 148504-34-1
Synonyms: Calcein acetoxymethyl ester
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10
10 Cited Publications
Cat. No.: HY-W250110
CAS No.: 9002-98-6
Target:
Research Areas:
Polyethylenimine (branched) (30% in water) is a organic macromolecule with high cationic-charge-density potential. Polyethylenimine (branched) (30% in water) can ensnare DNA as well as attach to cell membrane. Polyethylenimine (branched) (30% in water) also retains a substantial buffering capacity at virtually any pH .
10
10 Cited Publications
RI-1 is a RAD51 inhibitor, with IC50s ranging from 5 to 30 μM. RI-1 binds covalently to the surface of RAD51 protein at cysteine 319. RI-1 inactivates RAD51 by directly binding to a protein surface that serves as an interface between protein subunits in RAD51 filaments. RI-1 can disrupt homologous recombination in human cells .
6
6
6 Cited Publications
Cat. No.: HY-D0722
CAS No.: 124387-19-5
Synonyms: 5-(6)-Carboxyfluorescein diacetate; CFDA
6
6 Cited Publications
Target:
Research Areas:
PFM01, N-alkylated Mirin derivative, is a MRE11 endonuclease inhibitor. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR) .
5
5 Cited Publications
Synonyms: SHR3162; Fuzuloparib
Fluzoparib (SHR3162) is a potent and orally active PARP1 inhibitor (IC50=1.46±0.72 nM, a cell-free enzymatic assay) with superior antitumor activity. Fluzoparib selectively inhibits the proliferation of homologous recombination repair (HR)-deficient cells, and sensitizes both HR-deficient and HR-proficient cells to cytotoxic agents. Fluzoparib exhibits good pharmacokinetic properties in vivo and can be used for BRCA1/2-mutant relapsed ovarian cancer research .
5
3
3 Cited Publications
Cat. No.: HY-D0047
CAS No.: 79955-27-4
Synonyms: 5-Carboxyfluorescein diacetate
3
3 Cited Publications
Cat. No.: HY-D2346
Target:
Research Areas:
HBmito Crimson is a near-infrared Si-rhodamine probe and mitochondrial inner membrane voltage indicator. HBmito Crimson selectively accumulates in mitochondria through its lipophilic tail and positive charge, is activated by lipid bilayer interactions after chloride ion aggregation quenching, thereby staining cristae and resisting fixation/depolarization, and senses near-field potential through electrochromism and Nernstian redistribution. HBmito Crimson can be used for research on apoptosis (Apoptosis) and ferroptosis (Ferroptosis) .
2
2
1
Research Areas:
Polyethylenimine (branched) (MW 25000) is a organic macromolecule with high cationic-charge-density potential. Polyethylenimine (branched) (MW 25000) can ensnare DNA as well as attach to cell membrane .
1
1 Cited Publications
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .
1
1
1 Cited Publications
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Research Areas:
AOH1160 is a potent oral small molecule proliferating cell nuclear antigen (PCNA) inhibitor that interferes with DNA replication, blocks homologous recombination-mediated DNA repair, leads to cell cycle arrest and induces apoptosis .
1
1 Cited Publications
Cat. No.: HY-126972A
Purity: 98.02%
RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor with an IC50 of 11.1 μM. RI(dl)-2 TFA does not influence RAD51 binding to ssDNA and inhibits homologous recombination (HR) activity in human cells (IC50 of 3.0 μM) .
1
1
1 Cited Publications
Cat. No.: HY-P87059
Synonyms: DNA strand exchange and recombination protein with protease and nuclease activity antibody; lexB antibody; Protein recA antibody; recH antibody; Recombinase A antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
