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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
91 Results for "
cholesterol pathway
" in MedChemExpress (MCE) Product Catalog:
Products (91)
91 Results for "cholesterol pathway" in MCE Product Catalog:
18
18 Publications Verification
Cat. No.: HY-N0527
CAS No.: 14937-32-7
Synonyms: Penta-O-galloyl-β-D-glucose; 1,2,3,4,6-Pentagalloyl glucose
7
7 Cited Publications
Cat. No.: HY-N0010
CAS No.: 27741-01-1
Category:
Iridoids Terpenoids Plants Other Families Extract Endogenous metabolite Disease Research Fields Cancer
Target:
6
6
6 Cited Publications
Cat. No.: HY-N0430A
CAS No.: 1198398-71-8
5
5 Cited Publications
Category:
Alkaloids Microorganisms Immune System Disorder Other Diseases Disease markers Endogenous metabolite Disease Research Fields Cancer
Target:
4
4 Cited Publications
Cat. No.: HY-B1899A
CAS No.: 110026-03-4
Synonyms: Taurodeoxycholate sodium hydrate
3
3 Cited Publications
Cat. No.: HY-N1993
CAS No.: 82517-12-2
Category:
Flavonoids Metabolic Disease Plants Other Families Extract Disease Research Fields Isoflavones
Target:
2
2
2 Cited Publications
Cat. No.: HY-N10549
CAS No.: 83088-28-2
1
Target:
Research Areas:
PFM067, a potent and selective LXR agonist, specifically activates the cholesterol efflux arm of the LXR pathway without stimulating triglyceride synthesis. PFM067 has anti-inflammatory effects and can be used for the research of cholesterol homeostasis diabetes .
1
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Research Areas:
Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene in the cholesterol biosynthesis pathway . Lapaquistat acetate is effective at lowering low-density lipoprotein cholesterol, but it might cause liver damage. Lapaquistat acetate is used for hypercholesterolemia and mevalonate kinase deficiency (MKD) research .
1
1 Cited Publications
Synonyms: Farnesyl diphosphate ammonium
1
1 Cited Publications
Cat. No.: HY-N0468
CAS No.: 63279-13-0
Category:
Terpenoids Metabolic Disease Diterpenoids Plants Other Families Extract Disease Research Fields Sweeteners Food Research
Target:
1
Target:
Research Areas:
PD 128042 (CI 976) is a potent, orally active, and selective inhibitor of ACAT (acyl coenzyme A:cholesterol acyltransferase) with an IC50s of 73 nM. PD 128042 is also a potent LPAT (lysophospholipid acyltransferase) inhibitor. PD 128042 inhibits Golgi-associated LPAT activity (IC50=15 μM). PD 128042 inhibits multiple membrane trafficking steps, including ones found in the endocytic and secretory pathway .
1
Research Areas:
2,3-Oxidosqualene (Squalene oxide) is a sterol biosynthesis precursor intermediate.2,3-Oxidosqualene participates in cyclization pathways that form sterols and triterpenes, and contributes to introduction of their characteristic 3-hydroxyl group.2,3-Oxidosqualene forms metabolically from squalene in rat liver homogenates under sterol synthesis conditions.2,3-Oxidosqualene converts to sterols including cholesterol, lathosterol, and lanost-8-en-3β-ol in rat liver homogenates under anaerobic conditions .
1
1 Cited Publications
Cat. No.: HY-N0899
CAS No.: 11088-09-8
1
1 Cited Publications
Cat. No.: HY-176557
CAS No.: 907547-06-2
Research Areas:
NCI677397 is a USP24 inhibitor. NCI677397 increases lipid ROS, activates cholesterol and fatty acid biosynthesis, degrades ABC transporters, GPX4 and DHFR through the autophagy pathway, decreases the level of P-gp and ultimately leads to ferroptosis in drug-resistant cancer cells. NCI677397 can be used for the study of lung caner and brain cancer .
1
1 Cited Publications
Cat. No.: HY-N0857
CAS No.: 79233-15-1
Target:
Cat. No.: HY-N0466
CAS No.: 58543-16-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
