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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
coreceptor CCR5
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "coreceptor CCR5" in MCE Product Catalog:
1
1 Cited Publications
HIV-1 inhibitor-6 (compound 9), a diheteroarylamide-based compound, is a potent HIV-1 pre-mRNA alternative splicing inhibitor. HIV-1 inhibitor-6 blocks HIV replication. HIV-1 inhibitor-6 is active against wild-type HIV-1IIIB (subtype B, X4-tropic) and HIV-1 97USSN54 (subtype A, R5-tropic) with EC50s of 0.6 μM and 0.9 μM, respectively. HIV-1 inhibitor-6 inhibits HIV strains resistant to agents targeting HIV reverse transcriptase, protease, integrase, and coreceptor CCR5 with EC50s ranging from 0.9 to 1.5 μM .
Cat. No.: HY-149125
CAS No.: 71965-57-6
Synonyms: Ceramide trihexosides (porcine)
Target:
Research Areas:
Globotriaosylceramide porcine RBC (Ceramide trihexosides porcine) is a neutral glycosphingolipid belonging to the globoside series of erythrocytes, primarily isolated and extracted from porcine RBC. Globotriaosylceramide porcine RBC is a natural resistance factor against HIV-1 infection. Globotriaosylceramide porcine RBC blocks viral binding to CXCR4/CCR5 co-receptors through competitive binding to the V3 loop region of HIV-1 gp120, thereby inhibiting viral fusion and entry. Globotriaosylceramide porcine RBC is the major cell surface receptor for Shiga toxin. Globotriaosylceramide porcine RBC can be used for research on hemolytic uremic syndrome, HIV-1 infection, and Fabry disease .
Cat. No.: HY-174743
Target:
Research Areas:
Human CCR5 mRNA encodes the human C-C motif chemokine receptor 5 (CCR5) protein, a member of the beta chemokine receptor family. CCR5 is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. It may also play a role in granulocyte lineage proliferation and differentiation.
Cat. No.: HY-174751
Target:
Research Areas:
Human CCL5 mRNA encodes the human C-C motif chemokine ligand 5 (CCL5) protein, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. CCL5 is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.
Cat. No.: HY-P700540
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCR5; Chemokine (C-C Motif) Receptor 5 (Gene/Pseudogene); Prev. CMKBR5; C-C Motif Chemokine Receptor 5 A159A; CC-CKR-5; Chemokine Recptor CCR5 Delta32; C-C Chemokine Receptor Type 5; Mutant Chemokine Receptor CCR5; IDDM22; Mutant Chemokine Receptor 5; CKR-5; CC Chemokine Receptor 5; CD195; Chemokine Receptor 5; CKR5; CD195 Antigen; Mutant C-C Motif Chemokine Receptor; C-C CKR-5; Chemokine (C-C Motif) Receptor 5; Chemr13; HIV-1 Fusion coreceptor; CHEMR13; Chemokine Receptor CCR5; CCCKR5; CCR-5; C-C Motif Chemokine Receptor 5; C-C Motif Chemokine Receptor 5 (Gene/Pseudogene)
Species:
Mouse
Source:
P. pastoris
Cat. No.: HY-P702233
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCR5; Chemokine (C-C Motif) Receptor 5 (Gene/Pseudogene); Prev. CMKBR5; C-C Motif Chemokine Receptor 5 A159A; CC-CKR-5; Chemokine Recptor CCR5 Delta32; C-C Chemokine Receptor Type 5; Mutant Chemokine Receptor CCR5; IDDM22; Mutant Chemokine Receptor 5; CKR-5; CC Chemokine Receptor 5; CD195; Chemokine Receptor 5; CKR5; CD195 Antigen; Mutant C-C Motif Chemokine Receptor; C-C CKR-5; Chemokine (C-C Motif) Receptor 5; Chemr13; HIV-1 Fusion coreceptor; CHEMR13; Chemokine Receptor CCR5; CCCKR5; CCR-5; C-C Motif Chemokine Receptor 5; C-C Motif Chemokine Receptor 5 (Gene/Pseudogene)
Species:
Human
Source:
E. coli Cell-free
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
