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538 Results for "

cross-linking

" in MedChemExpress (MCE) Product Catalog:

Products (538)

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899

Cisplatin

899 Publications Verification

Cat. No.: HY-17394

CAS No.: 15663-27-1

Synonyms: cis-Platinum; CDDP; cis-Diaminodichloroplatinum

Target:

DNA Alkylator/Crosslinker Ferroptosis Autophagy Pyroptosis Lipoxygenase

Research Areas:

Cancer

Cisplatin (CDDP) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy .

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245

Oxaliplatin

245 Cited Publications

Cat. No.: HY-17371

CAS No.: 61825-94-3

Target:

DNA/RNA Synthesis Apoptosis

Research Areas:

Inflammation/Immunology Cancer

Oxaliplatin is a DNA synthesis inhibitor. Oxaliplatin causes DNA crosslinking damage, prevents DNA replication and transcription and induces apoptosis. Oxaliplatin can be used for cancer research .

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Rimiducid

61 Cited Publications

Cat. No.: HY-16046

CAS No.: 195514-63-7

Synonyms: AP1903

Target:

FKBP Apoptosis

Research Areas:

Cancer

Rimiducid (AP1903) is a dimerizer agent that acts by cross-linking the FKBP domains. Rimiducid (AP1903) dimerizes the Caspase 9 suicide switch and rapidly induces apoptosis.

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Ni-NTA His-Tag Purification Agarose

37 Cited Publications

Cat. No.: HY-K0210

MCE Ni-NTA His-Tag Purification Agarose, a 6% highly cross-linked agarose reagent, enables high-yield, high-purity purification of his-tagged proteins.

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6-Aminonicotinamide

25 Cited Publications

Cat. No.: HY-W010342

CAS No.: 329-89-5

Target:

NADPH Oxidase

Research Areas:

Cancer

6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP ⁺-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor (K_i=0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin (HY-17394), in killing cancer cells .

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