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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
cyclin-D3
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "cyclin-D3" in MCE Product Catalog:
6
6 Publications Verification
Cat. No.: HY-N0636
CAS No.: 13463-28-0
Synonyms: Eriodictyol 7-rutinoside; Eriodictyol 7-O-rutinoside
Category:
Rutaceae Extract Plant Flavonoids Flavonones Phenols Polyphenols Citrus limon (L.) Burm. F. Extract Disease Research Fields Cancer
Target:
2
Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.
2
2 Cited Publications
Cat. No.: HY-N7045
CAS No.: 142796-22-3
Category:
Silybum marianum (Linn.) Gaertn Extract Flavanonols Plant Flavonoids Phenols Polyphenols Compositae/Asteraceae Extract Disease Research Fields Cancer
Target:
2
2 Cited Publications
Synonyms: G1T38 dihydrochloride
Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 1 nM and 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.
Cat. No.: HY-N0636R
CAS No.: 13463-28-0
Synonyms: Eriodictyol 7-rutinoside (Standard); Eriodictyol 7-O-rutinoside (Standard)
Category:
Rutaceae Extract Plant Flavonoids Flavonones Phenols Polyphenols Citrus limon (L.) Burm. F. Extract
Target:
Cat. No.: HY-108907
CAS No.: 1446715-47-4
Target:
Research Areas:
SR-1277 is a potent, selective and ATP competitive CK1δ/ε inhibitor, with IC50s of 49 nM and 260 nM, respectively. SR-1277 also inhibits FLT3, CDK4/cyclin D1, CDK6/cyclin D3 and CDK9/cyclin K, with IC50s of 305 nM, 1340 nM, 311 nM and 109 nM, respectively. SR-1277 can be used for the research of cancer .
Cat. No.: HY-147409
CAS No.: 2075750-05-7
Ulecaciclib is an orally activitive inhibitor of cyclin-dependent kinase (CDK), with Ki values of 0.62 μM (CDK2/Cyclin A), 0.2 nM (CDK4/Cyclin D1), 3 nM (CDK6/Cyclin D3), and 0.63 μM (CDK7/Cyclin H), respectively. Ulecaciclib can cross blood brain barrier and has good pharmacokinetic characteristics [3].
Cat. No.: HY-172234
CAS No.: 2516247-98-4
Target:
Research Areas:
PF-06842874 is a CDK4/Cyclin D1 and CDK6/Cyclin D3 inhibitor (Ki values are 62 and 130 nM, respectively). PF-06842874 can be used in the research of pulmonary arterial hypertension and cancer .
Cat. No.: HY-P81456A
Synonyms: CCND3 ; G1/S-specific cyclin-D3
Cat. No.: HY-155180
CAS No.: 2685870-87-3
FD2056 is a potent and orally active PI3K inhibitor. FD2056 inhibits PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ with IC50s of 0.30, 0.80, 1.10, 0.42 nM. FD2056 also inhibits CDK2-CyclinA2 and CDK4-CyclinD3 with IC50 of 115.95 and 2782.15 nM. FD2056 inhibits breast cancer cell proliferation with IC50s of 1.06, 0.04, 1.40 μM for MDA-MB-231, MDA-MB-468, MCF-7 cells. FD2056 also induces cancer apoptosis and inhibits tumor growth .
Cat. No.: HY-P702957
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CCND3; G1/S-Specific cyclin-D3; cyclin D3; D3-Type cyclin
Species:
Human
Source:
E. coli
Cat. No.: HY-139449
CAS No.: 2380321-50-4
CDK4/6-IN-5 is a potent CDK4 and CDK6 inhibitor with Kis of 0.2 and 4.4 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively . (from patent WO2019207463A1 example A93).
Cat. No.: HY-N7045R
CAS No.: 142796-22-3
Cat. No.: HY-P701369
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK6; Cell Division Protein Kinase 6; cyclin Dependent Kinase 6; cyclin-Dependent Kinase 6; PLSTIRE; MCPH12; Serine/Threonine-Protein Kinase PLSTIRE; CDKN6; CCND3; G1/S-Specific cyclin-D3; cyclin D3; D3-Type cyclin
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701370
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK6; Cell Division Protein Kinase 6; cyclin Dependent Kinase 6; cyclin-Dependent Kinase 6; PLSTIRE; MCPH12; Serine/Threonine-Protein Kinase PLSTIRE; CDKN6; CCND3; G1/S-Specific cyclin-D3; cyclin D3; D3-Type cyclin
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702684
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK4; cyclin-Dependent Kinase 4; cyclin Dependent Kinase 4; cyclin-Dependent Kinase; PSK-J3; MCPH31; Cell Division Protein Kinase 4; CMM3; CCND3; G1/S-Specific cyclin-D3; cyclin D3; D3-Type cyclin
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
