13

13 Publications Verification

Target:

Research Areas:

Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .

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13

Nitrofurantoin sodium

13 Publications Verification

Cat. No.: HY-A0090A

CAS No.: 54-87-5

Target:

Antibiotic Bacterial

Research Areas:

Infection

Nitrofurantoin sodium is a potent and orally active antibacterial agent. Nitrofurantoin sodium acts as an antibiotic. Nitrofurantoin sodium can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .

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5

Tropisetron

5 Cited Publications

Cat. No.: HY-B0072

CAS No.: 89565-68-4

Synonyms: SDZ-ICS-930 free base

Target:

5-HT Receptor nAChR p38 MAPK NF-κB AP-1 Nuclear Factor of activated T Cells (NFAT) JAK

Research Areas:

Neurological Disease Inflammation/Immunology Cancer

Tropisetron is an orally active 5-HT3R antagonist (K_i = 5.3 nM) as well as being a potent and selective α7 nicotinic partial agonist (EC₅₀ = 1.3 μM). Tropisetron prevents phosphorylation and activation of the p38 MAPK. Tropisetron inhibits both IL-2 gene transcription and IL-2 synthesis in stimulated T cells. Tropisetron inhibits the binding to DNA and the transcriptional activity of NFAT and AP-1. Tropisetron is anti-inflammatory and antiemetic. Tropisetron has antitumor and neuroprotective effects. Tropisetron can be studied in research for diseases including hemorrhagic cystitis, chronic joint inflammation, lung cancer and chronic cerebral hypoperfusion .

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2

Sodium 2-mercaptoethanesulfonate

2 Cited Publications

Cat. No.: HY-13679

CAS No.: 19767-45-4

Purity: 99.78%

Synonyms: Mesnum

Target:

Biochemical Assay Reagents

Research Areas:

Inflammation/Immunology

Sodium 2-mercaptoethanesulfonate (Mesnum) is a thiol-containing urinary tract protective agent and aldehyde scavenger that detoxifies acrolein via its thiol group to form an inert thioether excreted in urine, and competitively inhibits human myeloperoxidase, thereby mitigating Cyclophosphamide (HY-17420)-induced cytogenetic damage. Sodium 2-mercaptoethanesulfonate can be used for research on hemorrhagic cystitis .

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2

Pentosan Polysulfate Sodium (W/W 43%)

2 Cited Publications

Cat. No.: HY-A0203A

CAS No.: 140207-93-8

Target:

HIV

Research Areas:

Infection Inflammation/Immunology Cancer

Pentosan Polysulfate Sodium is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also is a potent and selective anti-HIV agent. Pentosan Polysulfate Sodium is used for the treatment of interstitial cystitis .

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2

Phenazopyridine hydrochloride

2 Cited Publications

Cat. No.: HY-B0985

CAS No.: 136-40-3

Target:

TRP Channel

Research Areas:

Neurological Disease

Phenazopyridine hydrochlorideis a competitive SARM1 inhibitor, with IC₅₀ 145 μM. Phenazopyridine hydrochlorideis a TRPM8 antagonist. Phenazopyridine hydrochloride has a local anesthetic/analgesic effect. Phenazopyridine hydrochlorideis used to relieve painful symptoms of conditions such as cystitis and urethritis. Phenazopyridine hydrochloridecan promote neuronal differentiation and can also be used in the study of traumatic brain injury, peripheral neuropathy and neurodegenerative diseases .

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2

Phenazopyridine

2 Cited Publications

Cat. No.: HY-B0985A

CAS No.: 94-78-0

Target:

TRP Channel

Research Areas:

Neurological Disease

Phenazopyridine is a competitive SARM1 inhibitor, with IC₅₀ 145 μM. Phenazopyridine is a TRPM8 antagonist. Phenazopyridine has a local anesthetic/analgesic effect. Phenazopyridine is used to relieve painful symptoms of conditions such as cystitis and urethritis. Phenazopyridine can promote neuronal differentiation and can also be used in the study of traumatic brain injury, peripheral neuropathy and neurodegenerative diseases .

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