Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
de-iodination
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "de-iodination" in MCE Product Catalog:
3
Target:
Research Areas:
Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine . Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes .
Cat. No.: HY-W010696R
CAS No.: 5817-39-0
Synonyms: 3′,5′,3-Triiodothyronine (Standard)
Research Areas:
Reverse T3 (Standard) is the analytical standard of Reverse T3. This product is intended for research and analytical applications. Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine . Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes .
Cat. No.: HY-187086
CAS No.: 116754-87-1
Target:
Research Areas:
Iodofiltic acid is a terminal p-iodophenyl-substituted β-methyl-branched long-chain fatty acid and myocardial fatty acid metabolism inhibitor. Iodofiltic acid inhibits myocardial fatty acid metabolism via steric or chemical interference due to 3-position methyl branching. Iodofiltic acid shows significant myocardial uptake and prolonged retention in rats, with low in vivo deiodination and high blood levels .
Target:
Research Areas:
N-b-Hydroxyethyl oleyl imidazoline is a selective enzyme inhibitor targeting DIO, with an IC50 of 3.9 μM against human DIO3. N-b-Hydroxyethyl oleyl imidazoline binds to the catalytic domain of deiodinase and blocks the deiodination catalytic reaction of thyroid hormone molecules. N-b-Hydroxyethyl oleyl imidazoline can be used in studies related to the functional regulation of thyroid deiodinases .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
