country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

28 Results for "

depression-like behavior

" in MedChemExpress (MCE) Product Catalog:

Products (28)

Sort by :

Categories

By Targets

Products

Ciprofloxacin hydrochloride monohydrate

60 Publications Verification

Cat. No.: HY-B0356B

CAS No.: 86393-32-0

Synonyms: Bay-09867 hydrochloride monohydrate

Target:

Antibiotic Apoptosis Bacterial Reactive Oxygen Species (ROS) Topoisomerase Mitochondrial Metabolism Akt β-catenin

Research Areas:

Infection Cancer

Ciprofloxacin (Bay-09867) hydrochloride monohydrate is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin hydrochloride monohydrate exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin hydrochloride monohydrate inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin hydrochloride monohydrate induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin hydrochloride monohydrate can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Ciprofloxacin monohydrochloride

60 Publications Verification

Cat. No.: HY-B0356A

CAS No.: 93107-08-5

Synonyms: Bay-09867 monohydrochloride

Target:

Antibiotic Apoptosis Bacterial Reactive Oxygen Species (ROS) Topoisomerase Mitochondrial Metabolism Akt β-catenin

Research Areas:

Infection Cancer

Ciprofloxacin (Bay-09867) monohydrochloride is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin monohydrochloride exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin monohydrochloride inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin monohydrochloride induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin monohydrochloride can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Ciprofloxacin hydrochloride

60 Publications Verification

Cat. No.: HY-B0356C

CAS No.: 86483-48-9

Synonyms: Bay-09867 hydrochloride

Target:

Antibiotic Apoptosis Bacterial Reactive Oxygen Species (ROS) Topoisomerase Mitochondrial Metabolism Akt β-catenin

Research Areas:

Infection Cancer

Ciprofloxacin hydrochloride (Bay-09867 hydrochloride) is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin hydrochloride exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin hydrochloride inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin hydrochloride induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin hydrochloride can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .

Compare