23 Results for "

embryonic fibroblast

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "embryonic fibroblast" in MCE Product Catalog:

6
(±)-BI-D
(±)-BI-D
0 Images
6 Cited Publications
Cat. No.: HY-18601
CAS No.: 1416258-16-6
Target:  

HIV HIV Integrase

Research Areas:  

Infection

(±)-BI-D is a potent ALLINI (allosteric integrase inhibitor). (±)-BI-D binds integrase at the LEDGF/p75 binding site. (±)-BI-D inhibits HIV-Luc infection in cells (IC50: 0.16 μM in Psip1 knockout E9 mouse embryonic fibroblasts, 2.9 μM in wild-type E9 mouse embryonic fibroblasts) .
loading...
    loading...
View All Sizes
Magnesium chloride anhydrous, suitable for insect cell culture
Magnesium chloride anhydrous, suitable for insect cell culture
0 Images
Cat. No.: HY-Y1110H
CAS No.: 7786-30-3
Synonyms: Magnogene, suitable for insect cell culture
Magnesium chloride anhydrous, suitable for insect cell culture is an inorganic salt and cell culture medium component that can be used to prepare Tris buffer. Magnesium chloride anhydrous, suitable for insect cell culture is a component of Hunter's Thrips medium, which supports the in vitro culture of western flower thrip embryonic cells, and promotes the adhesion of tissue fragments/cells as well as the growth of fibroblast-like and epithelial-like cells .
loading...
    loading...
View All Sizes
CYT296
CYT296
0 Images
Cat. No.: HY-141591
CAS No.: 1799392-31-6
Purity:  99.80%
Target:  

Biochemical Assay Reagents

Research Areas:  

Others

CYT296 is a target chromatin de-condensation compound. CYT296 can improve the induction of induced pluripotent stem cell (iPSCs) mediated by defined factors (OSKM) and induce an open chromatin state in Mouse Embryonic Fibroblast (MEFs) to facilitate somatic cell reprogramming. CYT296 can be used for cell replacement therapies and drug screening research .
loading...
    loading...
View All Sizes
1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe
1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe
0 Images
Cat. No.: HY-115701
CAS No.: 154436-49-4
Synonyms: 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine; 15(S)-HpETE-SAPE; 15(S)-hydroperoxyeicostetraenoic acid-SAPE
Target:  

Ferroptosis

Research Areas:  

Inflammation/Immunology

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-Pe (SAPE) by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.
loading...
    loading...
View All Sizes
CD00509
CD00509
0 Images
Cat. No.: HY-W177546
CAS No.: 27430-18-8
Target:  

Phosphodiesterase (PDE) Apoptosis Caspase DNA/RNA Synthesis

Research Areas:  

Cancer

CD00509 is a tyrosyl-DNA phosphodiesterase (PDE) Tdp1 inhibitor with an IC50 of 0.71 μM. CD00509 increases DNA damage and promotes apoptosis of MCF-7 cells. CD00509 can sensitize breast cancer cells and wild-type murine embryonic fibroblasts (MEFs) to Camptothecin (CPT) (HY-16560). CD00509 can be used for the study of cancers such as breast cancer .
loading...
    loading...
View All Sizes
RBC6
RBC6
0 Images
Cat. No.: HY-125987
CAS No.: 381186-64-7
Purity:  98.88%
Target:  

Ras

Research Areas:  

Cancer

RBC6 is an inhibitor of GTPases RalA. RBC6 inhibits binding of Ral to its effector RALBP1. RBC6 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts, as well as anchorage-independent growth of human cancer celllines .
loading...
    loading...
View All Sizes
PPIase-Parvulin inhibitor
PPIase-Parvulin inhibitor
0 Images
Cat. No.: HY-128034
CAS No.: 64005-90-9
Purity:  99.79%
Target:  

PIN1

Research Areas:  

Cancer

PPIase-Parvulin inhibitor (compound B) is a cell-permeable inhibitor targeting PPIase Pin1 and Par14, with IC50s of 1.5 and 1.0 µM, respectively. PPIase-Parvulin inhibitor has anticancer activity and inhibits the growth and proliferation of mouse embryonic fibroblasts (MEFs) .
loading...
    loading...
View All Sizes
Kras4B G12D-IN-1
Kras4B G12D-IN-1
0 Images
Cat. No.: HY-153413
CAS No.: 2042365-85-3
Purity:  98.01%
Target:  

Ras

Research Areas:  

Cancer

Kras4B G12D-IN-1 is a Kras4B G12D inhibitor with anticancer effects. Kras4B G12D-IN-1 decreases Kras protein expression in mouse embryonic fibroblasts (MEF) expressing Kras4B G12D (WO2016179558A1, Comp 994566) .
loading...
    loading...
View All Sizes
UC-857993
UC-857993
0 Images
Cat. No.: HY-124514
CAS No.: 487001-04-7
Target:  

SOS1 Ras ERK

Research Areas:  

Cancer

UC-857993 is a selective SOS1-Ras inhibitor (Kd=14.7 μM, His6-SOS1cat), suppressing catalytic activity. UC-857993 also inhibits ERK and Ras activation, suppresses the growth of mouse embryonic fibroblasts (MEFs) .
loading...
    loading...
View All Sizes
HSV-1/HSV-2-IN-1
HSV-1/HSV-2-IN-1
0 Images
Cat. No.: HY-149022
CAS No.: 2490468-31-8
Target:  

HSV Orthopoxvirus

Research Areas:  

Infection

HSV-1/HSV-2-IN-1 (compound 7d) is a HSV-1 and HSV-2 inhibitor, with EC50s of 7.6, 7.6, 4, and 12 μM for HSV-1 (KOS), HSV-2 (G), HSV-1 TK - KOS ACV r and vaccinia virus in human embryonic lung fibroblast cell cultures .
loading...
    loading...
View All Sizes
C6 Urea Ceramide
C6 Urea Ceramide
0 Images
Cat. No.: HY-139062
CAS No.: 486991-52-0
Synonyms: C6 Ceramide (d18:1/6:0) Urea; Cer(d18:1/6:0) Urea; D-erythro-Urea-C6-Ceramide
Target:  

Apoptosis Ceramidase Autophagy β-catenin

Research Areas:  

Cancer

C6 Urea Ceramide (Cer(d18:1/6:0) Urea) is an inhibitor of neutral ceramidase. C6 Urea Ceramide increases total ceramide levels in wild-type mouse embryonic fibroblasts (MEFs) and HT-29 colon cancer cells. C6 Urea Ceramide (5-10 μM) inhibits proliferation of HT-29 cells and induces apoptosis and autophagy, but is not toxic to non-cancerous cells. C6 Urea Ceramide decreases total and phosphorylated β-catenin levels in HT-29 and HCT116 cells, and induces colocalization of β-catenin with the 20S proteasome. C6 Urea Ceramide (1.25, 2.5, and 5 mg/kg) reduced tumor growth and increased C16, C18, C20, and C24 ceramide levels in tumor tissues in the HT-29 mouse xenograft model.
loading...
    loading...
View All Sizes
Human FGF17 mRNA
Human FGF17 mRNA
0 Images
Cat. No.: HY-174705
Target:  

mRNA

Research Areas:  

Cancer

Human FGF17 mRNA encodes the human fibroblast growth factor 17 (FGF17) protein, a member of the fibroblast growth factor (FGF) family. FGF17 probably plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. It is also required for normal brain development.
loading...
    loading...
View All Sizes
Human FGF4 mRNA
Human FGF4 mRNA
0 Images
Cat. No.: HY-174696
Target:  

mRNA

Research Areas:  

Cancer

Human FGF4 mRNA encodes the human fibroblast growth factor 4 (FGF4) protein, a member of the fibroblast growth factor (FGF) family. FGF4 may play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation.
loading...
    loading...
View All Sizes
Human FGF3 mRNA
Human FGF3 mRNA
0 Images
Cat. No.: HY-174697
Target:  

mRNA

Research Areas:  

Cancer

Human FGF3 mRNA encodes the human fibroblast growth factor 3 (FGF3) protein, a member of the fibroblast growth factor (FGF) family. FGF3 may play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation.
loading...
    loading...
View All Sizes
Human FGF16 mRNA
Human FGF16 mRNA
0 Images
Cat. No.: HY-174706
Target:  

mRNA

Research Areas:  

Cardiovascular Disease

Human FGF16 mRNA encodes the human fibroblast growth factor 16 (FGF16) protein, a member of the fibroblast growth factor (FGF) family. FGF16 probably plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. It is also required for normal cardiomyocyte proliferation and heart development.
loading...
    loading...
View All Sizes
Human FGF9 mRNA
Human FGF9 mRNA
0 Images
Cat. No.: HY-174691
Target:  

mRNA

Research Areas:  

Cancer

Human FGF9 mRNA encodes the human fibroblast growth factor 9 (FGF9) protein, a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
loading...
    loading...
View All Sizes
Human FGF8 mRNA
Human FGF8 mRNA
0 Images
Cat. No.: HY-174692
Target:  

mRNA

Research Areas:  

Cancer

Human FGF8 mRNA encodes the human fibroblast growth factor 8 (FGF8) protein, a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
loading...
    loading...
View All Sizes
Human FGF7 mRNA
Human FGF7 mRNA
0 Images
Cat. No.: HY-174693
Target:  

mRNA

Research Areas:  

Cancer

Human FGF7 mRNA encodes the human fibroblast growth factor 7 (FGF7) protein, a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
loading...
    loading...
View All Sizes
RBC10
RBC10
0 Images
Cat. No.: HY-123464
CAS No.: 362503-73-9
Purity:  ≥98.0%
Target:  

Ras

Research Areas:  

Cancer

RBC10 is an anti-cancer agent. RBC10 inhibits the binding of Ral to its effector RALBP1. RBC10 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines .
loading...
    loading...
View All Sizes
Tembetarine chloride
Tembetarine chloride
0 Images
Cat. No.: HY-167835A
CAS No.: 2824-94-4
Category:  

Alkaloids Annonaceae Extract Other Alkaloids 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.