31 Results for "

eotaxin

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "eotaxin" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-103363
CAS No.: 247580-43-4
Purity:  99.58%
Research Areas:  

Inflammation/Immunology Cancer

SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM. SB-328437 can inhibit eosinophil migration induced by eotaxin, eotaxin-2, and monocyte chemotactic protein-4. In addition, SB-328437 can sensitize 5-FU (HY-90006)-resistant gastric cancer cells. SB-328437 can also reduce the recruitment of neutrophils to the lungs and pulmonary inflammation during acute inflammation. SB-328437 can be used in the research of inflammation-related diseases .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-N2609
CAS No.: 2196-14-7
7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid, which can be isolated from Glycyrrhiza uralensis. 7,4'-Dihydroxyflavone is eotaxin/CCL11 inhibitor and CBR1 inhibitor (IC50=0.28 μM). 7,4'-Dihydroxyflavone has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production . 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2.7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 µM .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P7760
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL24; CK-Beta-6; Prev. SCYA24; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 24; eotaxin-2; Eosinophil Chemotactic Protein 2; MPIF-2; Chemokine (C-C Motif) Ligand 24; MPIF2; Small-Inducible Cytokine A24; Myeloid Progenitor Inhibitory Factor 2; C
Species:  
Mouse
Source:  
E. coli
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P7160
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL11; Eosinophil Chemotactic Protein; Prev. SCYA11; MGC22554; eotaxin; Small-Inducible Cytokine A11; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 11 (eotaxin); C-C Motif Chemokine 11; Chemokine (C-C Motif) Ligand 11; C-C Motif Chemokine; C-C Mo
Species:  
Mouse
Source:  
E. coli
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P7161
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL24; CK-Beta-6; Prev. SCYA24; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 24; eotaxin-2; Eosinophil Chemotactic Protein 2; MPIF-2; Chemokine (C-C Motif) Ligand 24; MPIF2; Small-Inducible Cytokine A24; Myeloid Progenitor Inhibitory Factor 2; C
Species:  
Human
Source:  
E. coli
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P7766
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL24; CK-Beta-6; Prev. SCYA24; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 24; eotaxin-2; Eosinophil Chemotactic Protein 2; MPIF-2; Chemokine (C-C Motif) Ligand 24; MPIF2; Small-Inducible Cytokine A24; Myeloid Progenitor Inhibitory Factor 2; C
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-153991
CAS No.: 1355594-85-2
Purity:  98.01%
Target:  

STAT

Research Areas:  

Inflammation/Immunology

STAT6-IN-2 (Compound R-84) is a STAT6 inhibitor that can inhibit the tyrosine phosphorylation of STAT6. STAT6-IN-2 can also inhibit the secretion of eotaxin-3. STAT6-IN-2 can be used in the research of immune diseases and allergic inflammatory diseases such as asthma .
loading...
    loading...
Cat. No.: HY-P99474
CAS No.: 375348-49-5
Synonyms: CAT 213; iCo-008

Target:  

CCR

Research Areas:  

Inflammation/Immunology

Bertilimumab (CAT 213; iCo-008) is a human monoclonal antibody targeting eotaxin-1 (CCL11). Bertilimumab has the potential for allergic disorders research .
loading...
    loading...
Cat. No.: HY-110295
CAS No.: 688347-51-5
Target:  

GSNOR

Research Areas:  

Inflammation/Immunology

SPL-334 is a potent and selective S-Nitrosoglutathione reductase (GSNOR) inhibitor. SPL-334 causes a significant reduction in the production of Th2 cytokines IL-5 and IL-13 and the levels of the chemokine CCL11 (eotaxin-1) in the airways. SPL-334 can be used in research of allergic airway inflammation .
loading...
    loading...
Cat. No.: HY-160998
CAS No.: 671204-98-1
Target:  

CCR

Research Areas:  

Inflammation/Immunology

YM-344031 is an orally active antagonist for CCR3. YM-344031 inhibits binding of Eotaxin-1 and RANTES to CCR3, with IC50 of 3.0 and 16.3 nM. YM-344031 inhibits ligand-induced rise in intracellular Ca [2+] and the ligand-induced chemotaxis. YM-344031 inhibits eotaxin-1-induced changes in eosinophil morphology in macaques blood, and prevents allergic skin reactions in a mouse allergy model .
loading...
    loading...
Cat. No.: HY-N2609R
CAS No.: 2196-14-7
7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid, which can be isolated from Glycyrrhiza uralensis. 7,4'-Dihydroxyflavone is eotaxin/CCL11 inhibitor and CBR1 inhibitor (IC50=0.28 μM). 7,4'-Dihydroxyflavone has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production . 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2.7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 µM .
loading...
    loading...
Cat. No.: HY-RS16897
Research Areas:  

Others

Ccl11 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccl11 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-103360B
CAS No.: 202796-42-7
Target:  

CCR

Research Areas:  

Inflammation/Immunology

trans-J-113863 is a potent chemokine CCR1 and CCR3 receptor antagonist, and inhibits MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants with IC50 of 9.57 and 93.8 nM,respectively .
loading...
    loading...
Cat. No.: HY-144075
CAS No.: 3035893-19-4
Target:  

JAK

Research Areas:  

Inflammation/Immunology

JAK-IN-19 is a potent JAK inhibitor (PBMC IFNγ pIC50=7.2 and HLF Eotaxin pIC50=7.7). JAK-IN-19 has good retentive properties in the lung via mitigating being metabolized by Aldehyde Oxidase (AO), with diminished VEGFR2 selectivity (VEGFR2 pIC50=7.0, Aurora B pIC50=5.8) .
loading...
    loading...
Cat. No.: HY-P700963
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL11; Eosinophil Chemotactic Protein; Prev. SCYA11; MGC22554; eotaxin; Small-Inducible Cytokine A11; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 11 (eotaxin); C-C Motif Chemokine 11; Chemokine (C-C Motif) Ligand 11; C-C Motif Chemokine; C-C Mo
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-P992359
Synonyms: SHR-1905

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

GSK5784283 (SHR-1905) is a bivalent antibody against TSLP, which is applicable to research related to asthma. GSK5784283 has two Fab arms and is a humanized IgG1κ monoclonal antibody. GSK5784283 effectively reduces the levels of eosinophils, FeNO, TARC and eotaxin-3. GSK5784283 regulates FEV1 (forced expiratory volume in one second) .
loading...
    loading...
Cat. No.: HY-103363R
CAS No.: 247580-43-4
SB-328437 (Standard) is the analytical standard of SB-328437 (HY-103363). This product is intended for research and analytical applications. SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM. SB-328437 can inhibit eosinophil migration induced by eotaxin, eotaxin-2, and monocyte chemotactic protein-4. In addition, SB-328437 can sensitize 5-FU (HY-90006)-resistant gastric cancer cells. SB-328437 can also reduce the recruitment of neutrophils to the lungs and pulmonary inflammation during acute inflammation. SB-328437 can be used in the research of inflammation-related diseases .
loading...
    loading...
Cat. No.: HY-P7159
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL11; Eosinophil Chemotactic Protein; Prev. SCYA11; MGC22554; eotaxin; Small-Inducible Cytokine A11; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 11 (eotaxin); C-C Motif Chemokine 11; Chemokine (C-C Motif) Ligand 11; C-C Motif Chemokine; C-C Mo
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-P811052
Synonyms: Scya11, Ccl11, eotaxin, C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-P71901
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL11; Eosinophil Chemotactic Protein; Prev. SCYA11; MGC22554; eotaxin; Small-Inducible Cytokine A11; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 11 (eotaxin); C-C Motif Chemokine 11; Chemokine (C-C Motif) Ligand 11; C-C Motif Chemokine; C-C Mo
Species:  
Rat
Source:  
E. coli
loading...
    loading...