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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
ergot
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "ergot" in MCE Product Catalog:
14
14 Publications Verification
Synonyms: FCE-21336
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Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).
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Dihydroergotamine mesylate is a blood-brain barrier-permeable semi-synthetic ergot alkaloid, acting as a full agonist of 5-HT1B/1D receptors (Ki values of 0.3 nM and 2.5 nM, respectively; functional IC50 values of 2 nM and 2.2 nM, respectively). Dihydroergotamine mesylate inhibits Forskolin (HY-15371)-stimulated cAMP accumulation, possesses α-adrenergic receptor antagonistic activity and weak dopaminergic agonistic activity. It mediates intracranial cerebrovascular contraction, inhibits the release of neuropeptides such as CGRP/substance P, and suppresses neurogenic inflammation by activating 5-HT1B/1D receptors in the trigeminovascular system. Dihydroergotamine mesylate binds to the catalytic site of Trypanosoma cruzi trypanothione reductase and exhibits trypanocidal activity in vitro. Dihydroergotamine mesylate can be used in studies related to migraine and trypanosome infections .
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Lisuride is an orally active dopamine D2 receptors agonist. Lisuride, as an ergot derivative, can be used for the research of Parkinson's disease, migraine, and high prolactin levels .
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Lisuride (maleate) is a potent agonist of dopamine with a probably direct action on dopaminergic receptors. Lisuride (maleate) is an ergot derivative. Lisuride (maleate) releases the premenstrual mastalgia without significant side effects .
Cat. No.: HY-15296R
CAS No.: 81409-90-7
Synonyms: FCE-21336 (Standard)
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Cabergoline (Standard) is the analytical standard of Cabergoline. This product is intended for research and analytical applications. Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).
Cat. No.: HY-15296S1
CAS No.: 2738376-76-4
Synonyms: FCE-21336-d6
Cat. No.: HY-W001288
CAS No.: 1074-86-8
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Dihydroergotamine (DFN-19) is a blood-brain barrier-permeable semi-synthetic ergot alkaloid, acting as a full agonist of 5-HT1B/1D receptors (Ki values of 0.3 nM and 2.5 nM, respectively; functional IC50 values of 2 nM and 2.2 nM, respectively). Dihydroergotamine inhibits Forskolin (HY-15371)-stimulated cAMP accumulation, possesses α-adrenergic receptor antagonistic activity and weak dopaminergic agonistic activity. It mediates intracranial cerebrovascular contraction, inhibits the release of neuropeptides such as CGRP/substance P, and suppresses neurogenic inflammation by activating 5-HT1B/1D receptors in the trigeminovascular system. Dihydroergotamine binds to the catalytic site of Trypanosoma cruzi trypanothione reductase and exhibits trypanocidal activity in vitro. Dihydroergotamine can be used in studies related to migraine and trypanosome infections .
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Cat. No.: HY-106075
CAS No.: 83455-48-5
Synonyms: 2-Bromolisuride; Bromlisuride
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Bromerguride (2-Bromolisuride) is an analogue of the ergot dopamine agonist Lisuride (HY-12713). Bromerguride exhibits central antidopaminergic properties .
Cat. No.: HY-122495
CAS No.: 73625-62-4
Synonyms: rel-LY 171555 dihydrochloride; rel-LY 141865 dihydrochloride
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rel-Quinpirole (rel-LY 171555) dihydrochloride, an ergot compound, is a selective dopamine (DA) D2 receptor agonist. rel-Quinpirole dihydrochloride can be used for research on neurological diseases .
Cat. No.: HY-B0670AR
CAS No.: 6190-39-2
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Dihydroergotamine (mesylate) (Standard) is the analytical standard of Dihydroergotamine (mesylate). This product is intended for research and analytical applications. Dihydroergotamine mesylate is a BBB-permeable ergot alkaloid that can be used for the research of migraines .
Cat. No.: HY-15296A
CAS No.: 85329-89-1
Synonyms: FCE-21336 diphosphate
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Cabergoline diphosphate is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).
Cat. No.: HY-15296S
CAS No.: 1426173-20-7
Synonyms: FCE-21336-d5
Cat. No.: HY-13736
CAS No.: 87056-78-8
Synonyms: CV205-502
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Quinagolide (CV205-502) is a non-ergot dopamine D(2) receptor agonist that promotes dopamine activity. Quinagolide has shown effectiveness in modulating endocrine function, particularly in inhibiting disorders associated with dopamine deficiency. Quinagolide is used to suppress hyperprolactinemia and corresponding clinical symptoms, showing good efficacy. Quinagolide's biological activity enables its use as an important research compound in drug isolation and analysis .
Cat. No.: HY-W422431
CAS No.: 5878-43-3
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Cat. No.: HY-W751608
CAS No.: 548-43-6
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Cat. No.: HY-119997
CAS No.: 59032-40-5
Synonyms: CH 29-717
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Disulergine (CH 29-717) is an ergot alkaloid. Disulergine is a dopamine receptor agonist. Disulergine inhibits secretion of prolactin in rats. Disulergine inhibits growth hormone (GH) release .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
