1

Oxethazaine

1 Cited Publications

Cat. No.: HY-B0955

CAS No.: 126-27-2

Synonyms: Oxetacaine

Target:

HBV

Research Areas:

Neurological Disease

Oxethazaine (Oxetacaine), a precursor of phentermine?acidic, is an acid-resistent and orally active analgesic agent. Oxethazaine (Oxetacaine) has the potential for the relief of pain associated with?peptic ulcer disease?or?esophagitis .

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Cendakimab

1 Cited Publications

Cat. No.: HY-P99496

CAS No.: 2151032-62-9

Synonyms: RPC 4046; ABT 308; CC-93538

Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the IL-13 molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC₅₀s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases (e.g., asthma and eosinophilic esophagitis) .

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1

Anti-Mouse IL-18 Antibody (YIGIF74-1G7)

1 Cited Publications

Cat. No.: HY-P990220

Anti-Mouse IL-18 Antibody (YIGIF74-1G7) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-18. Anti-Mouse IL-18 Antibody (YIGIF74-1G7) can neutralize IL-18. Anti-Mouse IL-18 Antibody (YIGIF74-1G7) can be used for the researches of cancer, infection, inflammation and immunology, such as hepatocellular carcinoma and eosinophilic esophagitis .

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Linaprazan

Cat. No.: HY-100412

CAS No.: 248919-64-4

Purity: 99.61%

Synonyms: AZD0865

Target:

Proton Pump

Research Areas:

Cancer

Linaprazan (AZD0865) can inhibit H+,K+ -ATPase in the stomach through K+ competitive binding, (IC₅₀: 1.0 ± 0.2 μM), it has a strong inhibitory effect on acid. Linaprazan (AZD0865) can be used for research on reflux esophagitis with oral activity .

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Anti-Mouse IL-15 Antibody (AIO.3)

Cat. No.: HY-P990223

Anti-Mouse IL-15 Antibody (AIO.3) is a rat-derived IgG2a λ type antibody inhibitor, targeting to mouse IL-15. Anti-Mouse IL-15 Antibody (AIO.3) can neutralize IL-15. Anti-Mouse IL-15 Antibody (AIO.3) can be used for the researches of cancer, infection and inflammation, such as hepatitis virus infection and esophagitis .

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Linaprazan glurate

Cat. No.: HY-145578

CAS No.: 1228559-81-6

Purity: 99.67%

Synonyms: X842

Target:

Drug Intermediate Proton Pump

Research Areas:

Metabolic Disease

Linaprazan glurate (X842) is an orally atcive prodrug of Linaprazan (HY-100412) with a potent and prolonged inhibitory effect on gastric acid secretion. Linaprazan glurate is rapidly transformed by enzymatic cleavage into its active metabolite, linaprazan. Linaprazan glurate is a potassium-competitive acid blocker. Linaprazan glurate selectively inhibites acid formation from gastric H⁺/K⁺-ATPase in a potassium-dependent manner (IC₅₀ = 436.2 nM). Linaprazan glurate can be used for the studies of erosive esophagitis (EE) .

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Dectrekumab

Cat. No.: HY-P99846

CAS No.: 1528523-94-5

Synonyms: QAX576

Target:

Interleukin Related

Research Areas:

Inflammation/Immunology

Dectrekumab (QAX576) is a human monoclonal antibody that targets IL-13. Dectrekumab significantly improves intraepithelial esophageal eosinophil counts and dysregulated esophageal disease-related transcripts with Eosinophilic esophagitis (EoE) in a sustained manner and can be used for inflammation and immunology related research .

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Linaprazan mesylate

Cat. No.: HY-100412A

CAS No.: 855998-67-3

Synonyms: AZD-0865 mesylate

Target:

Proton Pump

Research Areas:

Cancer

Linaprazan mesylate can inhibit H+,K+ -ATPase in the stomach through K+ competitive binding. (IC 50: 1.0 ± 0.2 μM), it has a strong inhibitory effect on acid. Linaprazan (AZD0865) mesylate can be used for research on reflux esophagitis with oral activity .

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Oxethazaine (Standard)

Cat. No.: HY-B0955R

CAS No.: 126-27-2

Synonyms: Oxetacaine (Standard)

Target:

Reference Standards HBV

Research Areas:

Neurological Disease

Oxethazaine (Standard) is the analytical standard of Oxethazaine. This product is intended for research and analytical applications. Oxethazaine (Oxetacaine), a precursor of phentermine acidic, is an acid-resistent and orally active analgesic agent. Oxethazaine (Oxetacaine) has the potential for the relief of pain associated with peptic ulcer disease or esophagitis .

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Azeloprazole sodium

Cat. No.: HY-19865

CAS No.: 955095-47-3

Target:

Na+/K+ ATPase

Research Areas:

Inflammation/Immunology

Azeloprazole sodium is an orally active proton pump inhibitor. Azeloprazole sodium irreversibly binds to and blocks the proton pump (H ⁺/K ⁺-ATPase) on parietal cells, thereby inhibiting gastric acid secretion. Azeloprazole sodium is primarily metabolized by the CYP3A4 enzyme, and its pharmacokinetics and acid-suppressive effects are independent of CYP2C19 activity. Azeloprazole sodium can be used for research on acid-related diseases such as reflux esophagitis and gastroesophageal reflux disease .

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Linaprazan (Standard)

Cat. No.: HY-100412R

CAS No.: 248919-64-4

Synonyms: AZD0865 (Standard)

Target:

Reference Standards Proton Pump

Research Areas:

Cancer

Linaprazan (Standard) is the analytical standard of Linaprazan. This product is intended for research and analytical applications. Linaprazan (AZD0865) can inhibit H+,K+ -ATPase in the stomach through K+ competitive binding, (IC50: 1.0 ± 0.2 μM), it has a strong inhibitory effect on acid. Linaprazan (AZD0865) can be used for research on reflux esophagitis with oral activity .

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Azeloprazole

Cat. No.: HY-109023

CAS No.: 955095-45-1

Target:

Na+/K+ ATPase

Research Areas:

Inflammation/Immunology

Azeloprazole is an orally active proton pump inhibitor. Azeloprazole irreversibly binds to and blocks the proton pump (H ⁺/K ⁺-ATPase) on parietal cells, thereby inhibiting gastric acid secretion. Azeloprazole is primarily metabolized by the CYP3A4 enzyme, and its pharmacokinetics and acid-suppressive effects are independent of CYP2C19 activity. Azeloprazole can be used for research on acid-related diseases such as reflux esophagitis and gastroesophageal reflux disease .

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Azeloprazole potassium

Cat. No.: HY-109023A

CAS No.: 955095-50-8

Target:

Na+/K+ ATPase

Research Areas:

Inflammation/Immunology

Azeloprazole potassium is an orally active proton pump inhibitor. Azeloprazole potassium irreversibly binds to and blocks the proton pump (H ⁺/K ⁺-ATPase) on parietal cells, thereby inhibiting gastric acid secretion. Azeloprazole potassium is primarily metabolized by the CYP3A4 enzyme, and its pharmacokinetics and acid-suppressive effects are independent of CYP2C19 activity. Azeloprazole potassium can be used for research on acid-related diseases such as reflux esophagitis and gastroesophageal reflux disease .

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