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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
fast inactivation gating
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "fast inactivation gating" in MCE Product Catalog:
Target:
Research Areas:
AA43279 is an orally effective, blood-brain barrier-penetrant Nav1.1 voltage-gated sodium channel activator with an EC50 of 9.5 μM in HEK-293 cells. AA43279 inhibits fast inactivation and enhances sodium conductance. AA43279 can be used in research on schizophrenia and Dravet syndrome .
Research Areas:
N-Bromoacetamide is an ion channel modulator that modifies proteins by cleaving peptide bonds. N-Bromoacetamide prolongs sodium channel opening time, increases Na + influx, and eliminates fast inactivation of voltage-gated Na + channels. N-Bromoacetamide irreversibly eliminates the calcium-dependent component of calcium-activated potassium channel opening and reduces channel open probability. N-Bromoacetamide slows the inactivation of inactivating K + currents. N-Bromoacetamide also exhibits anti-enterovirus 71 (EV71) activity, inhibiting EV71 replication, reducing viral yield, and alleviating EV71-induced cytopathic effects. N-Bromoacetamide can be used in research on enterovirus infection .
Cat. No.: HY-189797
CAS No.: 3119060-02-2
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Research Areas:
Insecticidal agent 46 is a voltage-gated sodium channel (VGSC) modulator. Insecticidal agent 46 shifts fast inactivation gating toward hyperpolarization and impairs the fast inactivation gate. Insecticidal agent 46 can be used as an insecticide .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
