Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
fecundity
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "fecundity" in MCE Product Catalog:
Synonyms: IKI-7899
Target:
Research Areas:
Chlorfluazuron (IKI-7899) is a benzoylurea chitin synthesis inhibitor and a PPARγ agonist ligand that blocks the polymerization of UDP-N-acetylglucosamine by inhibiting chitin synthase, disrupting cuticle formation, molting, and embryonic development, thereby exerting ovicidal, larvicidal, and fecundity-reducing effects in insects. Chlorfluazuron is used in hepatotoxicity research .
Synonyms: BY-108330
Research Areas:
Spirotetramat (BY-108330) is an orally active Insecticide and lipid biosynthesis inhibitor. Spirotetramat regulates the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), with short-term exposure increasing their activities and long-term exposure altering their activities. Spirotetramat induces the activity and mRNA expression of carboxylesterase (CarE). Spirotetramat induces oxidative stress and lipid peroxidation in tadpoles. Spirotetramat is toxic to amphibian tadpoles and exhibits sublethal/non-lethal toxicity to amphibians. Spirotetramat causes death in immature psyllids, aphids, scale insects, mealybugs, whiteflies and thrips, and shows a high lethal rate against Cacopsylla pyri nymphs. Spirotetramat reduces the fecundity of Aphis gossypii. Spirotetramat induces tolerance in the offspring of exposed Aphis gossypii, and acts on Myzus persicae, Bemisia tabaci and Tetranychus urticae .
Cat. No.: HY-N16479
CAS No.: 134788-16-2
Category:
Plant Tetracyclic Triterpenoids Terpenoids Meliaceae Extract Azadirachta indica A. Juss. Extract
Target:
Cat. No.: HY-133204R
CAS No.: 71422-67-8
Synonyms: IKI-7899 (Standard)
Target:
Research Areas:
Chlorfluazuron (Standard) (IKI-7899 (Standard)) is the analytical standard of Chlorfluazuron (HY-133204). This product is intended for research and analytical applications. Chlorfluazuron (IKI-7899) is a benzoylurea chitin synthesis inhibitor and a PPARγ agonist ligand that blocks the polymerization of UDP-N-acetylglucosamine by inhibiting chitin synthase, disrupting cuticle formation, molting, and embryonic development, thereby exerting ovicidal, larvicidal, and fecundity-reducing effects in insects. Chlorfluazuron is used in hepatotoxicity research .
Cat. No.: HY-105714
CAS No.: 18588-57-3
Target:
Research Areas:
Etoprine is a potent orally active dihydrofolate reductase (DHFR) inhibitor. Etoprine competitively inhibits testicular DHFR to disrupt tetrahydrofolate and DNA synthesis in rapidly dividing cells. Etoprine acts as an antifertility agent in male mice and reduces fecundity in male rats .
Cat. No.: HY-187528
GPCR antagonist-2 is a GPCR antagonist with macrofilaricidal activity. GPCR antagonist-2 shows inhibitory effects on Brugia pahangi adult females and males (IC50 = 3.9 μM and 2.8 μM, respectively) and Onchocerca ochengi adult females and males (IC50 = 0.35 μM and 1.7 μM, respectively). GPCR antagonist-2 reduces B. pahangi worm burden and affects female fecundity and embryogenesis, downregulates GPCR expression in surviving adult female worms and can be used for the study of filarial infections, including onchocerciasis (river blindness) .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
