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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
focal epilepsy
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "focal epilepsy" in MCE Product Catalog:
7
Target:
Research Areas:
Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na + channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al .
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1 Cited Publications
Synonyms: XEN1101; Encukalner
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Research Areas:
Azetukalner (XEN1101) is a selective and orally active Kv7.2/Kv7.3 potassium channel opener with an EC50 of 27 nM. Azetukalner is approximately 4-fold more selective for Kv7.2/7.3 over Kv7.3/7.5 (EC50 of 94 nM) and Kv7.4 (EC50 of 113 nM) channels. Azetukalner exhibits a selectivity >100-fold for Kv7 channels over other ion channels and receptors. Azetukalner can be used for the study of focal epilepsy .
1
1 Cited Publications
Synonyms: NBI-921352; XEN901
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Research Areas:
Zandatrigine (NBI-921352; XEN901) is a selective, orally active, voltage-gated sodium channel NaV1.6/SCN8A inhibitor that can penetrate the blood-brain barrier. Zandatrigine inhibits sodium influx by non-covalently binding to the VSD4 structure of NaV1.6, blocking the persistent and resuscitative currents under pathological conditions. Zandatrigine can reduce neuronal hyperexcitability and reduce epileptic seizures. Zandatrigine is 134-756-fold selective for other isoforms such as NaV1.1 and NaV1.2, and has minimal effect on NaV1.1 expressed by inhibitory interneurons. Zandatrigine can be used to study NaV1.6-mediated neuroexcitability diseases such as SCN8A-related developmental epileptic encephalopathy (SCN8A-DEE) and adult focal epilepsy .
Cat. No.: HY-159819
CAS No.: 2392951-18-5
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Research Areas:
Vormatrigine is an orally active sodium channel inhibitor with anti-epileptic activity. Vormatrigine can be used to study human focal and generalized epilepsy .
Cat. No.: HY-B0495R
CAS No.: 84057-84-1
Synonyms: LTG (Standard); BW430C (Standard)
Target:
Research Areas:
Lamotrigine (Standard) is the analytical standard of Lamotrigine. This product is intended for research and analytical applications. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na + channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al .
Cat. No.: HY-B0495S4
CAS No.: 1188265-38-4
Synonyms: LTG-13C3; BW430C-13C3
Cat. No.: HY-B0495S5
CAS No.: 1132746-94-1
Synonyms: LTG-d3; BW430C-d3
Cat. No.: HY-B0495S3
CAS No.: 2483830-10-8
Cat. No.: HY-110032
CAS No.: 113170-86-8
Synonyms: LTG isethionate; BW430C isethionate
Target:
Research Areas:
Lamotrigine (BW430C) isethionate is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine isethionate selectively blocks voltage-gated Na + channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine isethionate can be used for the research of epilepsy, focal seizure, et al .
Cat. No.: HY-B0495S1
CAS No.: 2517756-06-6
Synonyms: LTG-13C,d3; BW430C-13C,d3
Cat. No.: HY-B0495A
CAS No.: 375347-20-9
Synonyms: LTG hydrate; BW430C hydrate
Target:
Research Areas:
Lamotrigine hydrate is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine hydrate selectively blocks voltage-gated Na + channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine hydrate can be used for the research of epilepsy, focal seizure, et al .
Cat. No.: HY-B0495S7
CAS No.: 2140316-15-8
Synonyms: LTG-13C; BW430C-13C
Cat. No.: HY-B0495S
CAS No.: 1246815-13-3
Synonyms: LTG-13C3,d3; BW430C-13C3,d3
Cat. No.: HY-B0495S8
Synonyms: LTG-13C7,15N; BW430C-13C7,15N
Cat. No.: HY-B0495S6
Synonyms: LTG-13C2,15N2,d3; BW430C-13C2,15N2,d3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
