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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
91 Results for "
follicle
" in MedChemExpress (MCE) Product Catalog:
Products (91)
91 Results for "follicle" in MCE Product Catalog:
5
5 Cited Publications
BSJ-03-123 is a selective PROTAC degrader of CDK6. BSJ-03-123 degrades CDK6, thereby inhibiting Rb S780 phosphorylation and inducing G1 phase arrest, while remodeling cell cycle and transcriptional signaling, with no effect on CDK4-dependent cancer cells. BSJ-03-123 reduces CDK6 protein levels in mouse ovarian tissues, increases the proportion of primordial follicles, and induces granulosa cell apoptosis, without impairing the ability of oocytes to resume meiosis and mature to the MII stage. BSJ-03-123 alleviates uveitis by blocking the HDACs-CDK6/ID2 axis. BSJ-03-123 can be used in studies related to acute myeloid leukemia, mantle cell lymphoma and autoimmune uveitis .
5
5 Cited Publications
Cat. No.: HY-P74133
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CGA; Anterior Pituitary Glycoprotein Hormones Common Subunit Alpha; Glycoprotein Hormones, Alpha Polypeptide; follicle-Stimulating Hormone Alpha Subunit; Glycoprotein Hormones Alpha Chain; Chorionic Gonadotropin, Alpha Polypeptide; GPA1; follicle-Stimulat
Species:
Human
Source:
HEK293
2
Target:
Research Areas:
Cetrorelix (SB-75) acetate is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix acetate inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix acetate prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix acetate is applicable for fertility assistance research .
2
Target:
Research Areas:
Cetrorelix (SB-75) is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix is applicable for fertility assistance research .
2
2 Cited Publications
Cat. No.: HY-P700159AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: INHBA; follicle-Stimulating Hormone-Releasing Protein; Inhibin Subunit Beta A; Erythroid Differentiation Factor; Inhibin Beta A Chain; Inhibin Beta A Subunit; Activin Beta-A Chain; FSH-Releasing Protein; Inhibin, Beta A (Activin A, Activin AB Alpha Polype
Species:
Human
Rat
Mouse
Source:
E. coli
1
1 Cited Publications
Category:
1
1 Cited Publications
Synonyms: Aminourea hydrochloride; Hydrazinecarboxamide hydrochloride
Target:
Research Areas:
Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase (SSAO). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles .
1
1 Cited Publications
Cat. No.: HY-P3343A
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P703702
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CGA; Anterior Pituitary Glycoprotein Hormones Common Subunit Alpha; Glycoprotein Hormones, Alpha Polypeptide; follicle-Stimulating Hormone Alpha Subunit; Glycoprotein Hormones Alpha Chain; Chorionic Gonadotropin, Alpha Polypeptide; GPA1; follicle-Stimulat
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70237
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CGA; Anterior Pituitary Glycoprotein Hormones Common Subunit Alpha; Glycoprotein Hormones, Alpha Polypeptide; follicle-Stimulating Hormone Alpha Subunit; Glycoprotein Hormones Alpha Chain; Chorionic Gonadotropin, Alpha Polypeptide; GPA1; follicle-Stimulat
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P3343
CAS No.: 142154-55-0
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P73241
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: INHBA; follicle-Stimulating Hormone-Releasing Protein; Inhibin Subunit Beta A; Erythroid Differentiation Factor; Inhibin Beta A Chain; Inhibin Beta A Subunit; Activin Beta-A Chain; FSH-Releasing Protein; Inhibin, Beta A (Activin A, Activin AB Alpha Polype
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P703994
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: INHBA; follicle-Stimulating Hormone-Releasing Protein; Inhibin Subunit Beta A; Erythroid Differentiation Factor; Inhibin Beta A Chain; Inhibin Beta A Subunit; Activin Beta-A Chain; FSH-Releasing Protein; Inhibin, Beta A (Activin A, Activin AB Alpha Polype
Species:
Human
Source:
HEK293
Target:
Research Areas:
Thyroglobulin is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle. Thyroglobulin activates Akt kinase activity in FRTL-5 thyroid cell .
Synonyms: Vinylcyclohexene diepoxide
Research Areas:
Neurological Disease Inflammation/Immunology Endocrinology Cancer
4-Vinylcyclohexene dioxide (4-Vinylcyclohexene diepoxide) is an orally active metabolite of 4-vinylcyclohexene. 4-Vinylcyclohexene dioxide induces Apoptosis, increases intracellular ROS, and activates the PI3K/Akt/mTOR pathway. 4-Vinylcyclohexene dioxide selectively damages small ovarian follicles, inhibits granulosa cell function, and disrupts the male reproductive system. 4-Vinylcyclohexene dioxide can be used in the study of premature ovarian insufficiency, reproductive toxicity, and related fertility disorders .
Category:
Human Gut Microbiota Metabolites Natural Products Other Diseases Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-W129161
CAS No.: 827306-88-7
Target:
Research Areas:
Synonyms: FPL 59002
Target:
Research Areas:
Nedocromil (FPL 59002) is a mast cell stabilizer and an inhibitor of IL-8 production. Nedocromil inhibits mast cell degranulation and collagen synthesis induced by activated mast cells, indirectly interfering with IL-1β signaling. Nedocromil reduces conjunctival eosinophil infiltration and improves the cutaneous manifestations of chronic graft-versus-host disease (including reducing fibrosis, loss of fat and hair follicles, and inflammatory infiltration). Nedocromil can be used in research on chronic graft-versus-host disease, asthma, and allergic conjunctivitis .
Cat. No.: HY-P1628
CAS No.: 124904-93-4
Target:
Research Areas:
Target:
Research Areas:
FSHR agonist 1 is a high affinity and allosteric follicle stimulating hormone receptor (FSHR) agonist with a pEC50 of 7.72. FSHR agonist 1 formes extensive interactions with the TMD to directly activate FSHR .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
