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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
glucose intolerance
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "glucose intolerance" in MCE Product Catalog:
54
54 Publications Verification
Cat. No.: HY-B0445A
CAS No.: 20111-18-6
Synonyms: β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium
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Exicorilant (CORT 125281) is a selective and oral active glucocorticoid receptor (GR) antagonist, with a Ki value of 7 nM . Exicorilant (CORT 125281) has potential to overcome adiposity, glucose intolerance and dyslipidaemia .
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CPT-157633, a difluoro-phosphonomethyl phenylalanine derivative, and is a PTP1B inhibitor. CPT-157633 prevents binge drinking-induced glucose intolerance .
Cat. No.: HY-W009417
CAS No.: 77-54-3
Category:
Plant Terpenoids Cunninghamia lanceolata var. konishii Extract Sesquiterpenes Metabolic Disease Disease Research Fields Taxodiaceae Extract
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Cat. No.: HY-N7912
CAS No.: 35910-16-8
Synonyms: (2S)-Pterosin A
Cat. No.: HY-P5390A
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Synonyms: GLP-1 receptor agonist 11
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Cardiovascular Disease Metabolic Disease Inflammation/Immunology
GLP-1 receptor agonist 11 is a GLP-1 receptor agonist .GLP-1 receptor agonist 11 activates the GLP-1 receptor .GLP-1 receptor agonist 11 can be used for the research of diabetes, non-alcoholic fatty liver disease, glucose intolerance, dyslipidemia, syndrome x, arteriosclerosis, hypertension, obesity, hepatic fibrosis, cirrhosis, somnolence, hyperglycemia, hyperlipidemia, atherosclerosis, hypertriglyceridemia, type 1 diabetes, type 2 diabetes, diabetic dyslipidemia .
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Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology
17-HDHA is a DHA-derived specialized pro-resolving mediator (SPM). 17-HDHA inhibits NF-κB activation by activating PPARγ and upregulating IκBα, targets FPR2 and Bcl-6, and also acts as a precursor of RvD1 and PD1. 17-HDHA inhibits pulmonary artery smooth muscle cell proliferation, regulates the expression of adiponectin, GLUT-4 and inflammatory cytokines, suppresses IgE production by B cells and promotes antibody secretion. 17-HDHA reduces adipose tissue inflammation, improves insulin sensitivity and glucose tolerance, alleviates pathological processes associated with pulmonary hypertension, and enhances antibody responses and virus neutralizing activity against influenza HA. 17-HDHA can be used in research related to obesity-associated inflammation, insulin resistance, glucose intolerance, pulmonary hypertension and influenza virus infection .
Cat. No.: HY-134191
CAS No.: 1817737-04-4
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Cryptochrome modulator 1 (Compound 50) is a cryptochrome modulator. Cryptochrome modulator 1 reduces glucose intolerance in diabetic mice .
Cat. No.: HY-P3866
CAS No.: 14317-68-1
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FK614 is an orally active, non-thiazolidinedione (TZD) type, and selective PPARγ modulator (SPPARM). FK614 functions as a PPARγ agonist with potent anti-diabetic activity in vivo. FK614 has different effects on the activation of PPARγ at each stage of adipocyte differentiation. FK614 can be used for the research of hyperglycemia, hypertriglyceridemia, glucose intolerance and type 2 diabetes .
Cat. No.: HY-P5390
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Cat. No.: HY-123765
CAS No.: 701232-94-2
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JTT-553 is a DGAT1 inhibitor (IC50: 2.38 nM). JTT-553 reduces plasma concentrations of glucose, insulin, non-esterified fatty acids (NEFA), total cholesterol (TC), and hepatic triglycerides (TG). JTT-553 improves insulin-dependent glucose uptake and glucose intolerance in adipose tissue of DIO mice. JTT-553 reduces TNF-α mRNA levels and increases GLUT4 mRNA levels in adipose tissue of KK-Ay mice. JTT-553 improves adipose tissue insulin resistance and systemic glucose metabolism by reducing body weight. JTT-553 can be used in the study of obesity and type 2 diabetes mellitus (T2DM) .
Cat. No.: HY-W009417R
CAS No.: 77-54-3
Cat. No.: HY-P11881
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Cat. No.: HY-N8250
CAS No.: 928205-59-8
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Plant Simple Phenylpropanols Phenylpropanoids Polygonaceae Extract Fallopia multiflora (Thunb.) Harald. Extract
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Cat. No.: HY-111469R
CAS No.: 888213-72-7
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CPT-157633 (Standard) is the analytical standard of CPT-157633 (HY-111469). This product is intended for research and analytical applications. CPT-157633, a difluoro-phosphonomethyl phenylalanine derivative, and is a PTP1B inhibitor. CPT-157633 prevents binge drinKing-induced glucose intolerance .
Cat. No.: HY-P11880
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Cat. No.: HY-182280
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BDM71230 is an orally active inducer of insulin-degrading enzyme (IDE), with an EC50 of 1.9 μM against human IDE. BDM71230 binds to the interface of IDE dimers and enhances the catalytic activity of IDE via steric effects. BDM71230 can potentiate the hydrolytic effect of IDE on insulin and slightly attenuate the hypoglycemic effect of insulin. BDM71230 serves as a pharmacological tool for investigating IDE function and is applicable to studies related to glucose intolerance .
Cat. No.: HY-183489
CAS No.: 1357266-44-4
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TAAR1-agonist-4 is a TAAR1 agonist and oral hypoglycemic agent with an EC50 of 0.0046 μM for TAAR1. TAAR1-agonist-4 alleviates antipsychotic-related metabolic side effects, improves negative and cognitive symptoms, and reduces drug abuse behaviors. TAAR1-agonist-4 is applicable to research on schizophrenia, acute manic episodes associated with bipolar disorder, and glucose intolerance .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
