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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
hCCR4
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "hCCR4" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
CCR4 antagonist 4 (compound 22) is a selective and potent antagonist of the CC chemokine receptor-4 (CCR4), with an IC50 of 0.02 μM. CCR4 antagonist 4 also blocks MDC-mediated chemotaxis (IC50: 0.007 μM) and Ca 2+ mobilization (IC50: 0.003 μM). CCR4 antagonist 4 can be used for allergic inflammation research .
1
1 Cited Publications
Cat. No.: HY-P7196
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL16; Small-Inducible Cytokine A16; Prev. SCYA16; Liver-Expressed Chemokine; LCC-1; C-C Motif Chemokine 16; HCC-4; Chemokine LEC; NCC-4; Monotactin-1; LMC; ILINCK; Mtn-1; NCC4; CKb12; Liver CC Chemokine-1; SCYL4; C-C Motif Chemokine; LEC; New CC Chemokin
Species:
Human
Source:
CHO
Target:
Research Areas:
CCR4 antagonist 3 is a potent chemokine receptor 4 (CCR4) antagonist with an IC50 value of 1.7 μM for [ 125I]TARC (thymus and activation regulated chemokine). CCR4 antagonist 3 inhibits binding of radiolabeled TARC and macrophage-derived chemokine (MDC) to CCR4 receptors on the surface of CEM cells. CCR4 antagonist 3 also inhibits the in vitro migration of CEM cells mediated by TARC (IC50 = 6.4 μM) .
Cat. No.: HY-125836
CAS No.: 2206788-99-8
Target:
Research Areas:
CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues.
CCR4 antagonist 2 (Compound 31) exhibits IC50 values of Ca 2+flux and (chemotaxis) CTX are 40 nM and 70 nM, respectively .
Cat. No.: HY-174744
Target:
Research Areas:
Human CCR4 mRNA encodes the human C-C motif chemokine receptor 4 (CCR4) protein, a member of G protein-coupled receptors family. CCR4 is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
Cat. No.: HY-RS02157
Target:
Research Areas:
CCR4 Human Pre-designed siRNA Set A contains three designed siRNAs for CCR4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02158
Target:
Research Areas:
Ccr4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccr4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02159
Target:
Research Areas:
Ccr4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccr4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P700399
Purity: Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: CCR4; CKR4; C-C Motif Chemokine Receptor 4; C-C Chemokine Receptor Type 4; CC-CKR-4; C-C CKR-4; CMKBR4; CCR-4; K5-5; CDNA FLJ75821, Highly Similar To Homo Sapiens Chemokine (C-C Motif) Receptor 4 (CCR4), MRNA; Chemokine (C-C Motif) Receptor 4; Chemokine (
Species:
Human
Source:
HEK293
Cat. No.: HY-P702606
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCR4; CKR4; C-C Motif Chemokine Receptor 4; C-C Chemokine Receptor Type 4; CC-CKR-4; C-C CKR-4; CMKBR4; CCR-4; K5-5; CDNA FLJ75821, Highly Similar To Homo Sapiens Chemokine (C-C Motif) Receptor 4 (CCR4), MRNA; Chemokine (C-C Motif) Receptor 4; Chemokine (
Species:
Human
Source:
E. coli Cell-free
Cat. No.: HY-P704078
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: EDN3; PPET3; Endothelin 3; ET-3; Preproendothelin-3; HSCR4; Endothelin-3; WS4B; ET3
Species:
Human
Source:
P. pastoris
Cat. No.: HY-P86816
Synonyms: BTG1 binding factor 1 antibody; BTG1-binding factor 1 antibody; CAF 1 antibody; CAF-1 antibody; CAF1 antibody; Carbon catabolite repressor protein (CCR4) associative factor 1 antibody; CCR4 associated factor 1 antibody; CCR4 NOT transcription complex subunit 7 antibody; CCR4-associated factor 1 antibody; CCR4-NOT transcription complex subunit 7 antibody; BTG1 binding factor 1 antibody; BTG1-binding factor 1 antibody; CAF 1 antibody; CAF-1 antibody; CAF1 antibody; Carbon catabolite repressor protein (CCR4) associative factor 1 antibody; CCR4 associated factor 1 antibody; CCR4 NOT transcription complex subunit 7 antibody; CCR4-associated factor 1 antibody; CCR4-NOT transcription complex subunit 7 antibody; CNOT 7 antibody; Cnot7 antibody; CNOT7_HUMAN antibody; hCAF 1 antibody; hCAF1 antibody;
Cat. No.: HY-P7197
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL16; Small-Inducible Cytokine A16; Prev. SCYA16; Liver-Expressed Chemokine; LCC-1; C-C Motif Chemokine 16; HCC-4; Chemokine LEC; NCC-4; Monotactin-1; LMC; ILINCK; Mtn-1; NCC4; CKb12; Liver CC Chemokine-1; SCYL4; C-C Motif Chemokine; LEC; New CC Chemokin
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
