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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
hMR
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "hMR" in MCE Product Catalog:
56
56 Publications Verification
Synonyms: hMR-1275; Alvocidib; L86-8275
Flavopiridol (Alvocidib) is a broad spectrum and competitive inhibitor of CDKs, inhibiting CDK1, CDK2, CDK4 with IC50s of 30, 170, 100 nM, respectively.
56
56 Publications Verification
Synonyms: Alvocidib Hydrochloride; L86-8275 Hydrochloride; hMR-1275 Hydrochloride
Flavopiridol Hydrochloride (Alvocidib Hydrochloride) is a broad inhibitor of CDK, competing with ATP to inhibit CDKs including CDK1, CDK2, CDK4 with IC50s of 30, 170, 100 nM, respectively.
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Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma .
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2 Cited Publications
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HMR 1556, a chromanol derivative, is a potent IKs blocker with IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively .
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Ataciguat (HMR-1766) is a nitric oxide-independent soluble guanylate cyclase (sGC) activator. Ataciguat is able to activate the ferric heme-iron redox form of sGC that stimulate the production of cyclic GMP (cGMP). Ataciguat exhibits vasodilator effects .
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Pralnacasan (VX-740) is a potent, selective, non-peptide and orally active interleukin-1β converting enzyme (ICE, caspase 1) inhibitor with a Ki of 1.4 nM. Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan has the potential for osteoarthritis and rheumatoid arthritis treatment .
Cat. No.: HY-109555
CAS No.: 207748-29-6
Synonyms: hMR 1964
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Synonyms: PSK-3841; hMR-3841
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RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 has a dramatic effect on hair regrowth .
Synonyms: hMR 1098
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Clamikalant sodium (HMR 1098) is an ATP-sensitive potassium (KATP) channel blocker. Clamikalant sodium can be used for the research of arrhythmia .
Cat. No.: HY-RS09550
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NR4A1 Human Pre-designed siRNA Set A contains three designed siRNAs for NR4A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-106256
CAS No.: 214140-47-3
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HMR-3339 is a new selective estrogen receptor modulator. HMR-3339 reduces total cholesterol, low-density lipoprotein cholesterol, and homocysteine. HMR-3339 corrects bone alterations induced by ovariectomy .
Cat. No.: HY-RS16573
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Nr4a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nr4a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-19656
CAS No.: 262376-75-0
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HMR1426 is an orally active, potent gastric emptying inhibitor. HMR1426 reduces food intake and the rate of gastric emptying, decreases body weight and fat mass and shows an anorectic potential in rats. HMR1426 has the potential for obesity research .
Cat. No.: HY-P0068
CAS No.: 227472-48-2
Synonyms: hMR 3270; IP960; NXL201
Cat. No.: HY-A0062R
CAS No.: 191114-48-4
Synonyms: hMR3647 (Standard); RU66647 (Standard)
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Telithromycin (Standard) is the analytical standard of Telithromycin. This product is intended for research and analytical applications. Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma .
Cat. No.: HY-W008125S
Synonyms: Methyl acetobromo-α-D-glucuronate-13C6 methyl ester
Cat. No.: HY-RS08641
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MRC1 Human Pre-designed siRNA Set A contains three designed siRNAs for MRC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-106369R
CAS No.: 223749-46-0
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HMR 1556 (Standard) is the analytical standard of HMR 1556 (HY-106369). This product is intended for research and analytical applications. HMR 1556, a chromanol derivative, is a potent IKs blocker with IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively .
Cat. No.: HY-106165
CAS No.: 202415-99-4
Synonyms: IPL 576092
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HMR-4011A (IPL 576092) is an orally active, chemically modified version of Contignasterol. HMR-4011A can be isolated from sponge Petrosia contignata. HMR-4011A reduces inflammation. HMR-4011A can be used in the research of asthma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
