5 Results for "

hPTP1B

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "hPTP1B" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N2451
CAS No.: 33037-46-6
Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC50 of 26.6 μM [1].
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Cat. No.: HY-N0312
CAS No.: 113443-70-2
Rhein-8-glucoside calcium, an anthraquinone compound, is isolated from the EtOH extract of the roots of Saussurea lappa. Rhein-8-glucoside calcium is an hPTP1B inhibitor, with an IC50 of 11.5 μM. Rhein-8-glucoside calcium has antibacterial effects [1] .
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Cat. No.: HY-139641
CAS No.: 724451-35-8
Target:  

Phosphatase

Research Areas:  

Metabolic Disease

PTP1B-IN-14 is an allosteric, selective PTP1B inhibitor with an IC50 of 0.72 μM against hPTP1B. PTP1B-IN-14 can be used for research on type 2 diabetes and obesity [1].
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Cat. No.: HY-N2451R
CAS No.: 33037-46-6
Aloe-emodin-8-O-β-D-glucopyranoside (Standard) is the analytical standard of Aloe-emodin-8-O-β-D-glucopyranoside. This product is intended for research and analytical applications. Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC50 of 26.6 μM [1].
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Cat. No.: HY-N20734
CAS No.: 64527-08-8
Synonyms: Polygalacin
Rhamnazin 3-O-rutinoside (Polygalacin) is a flavonoid compound. Rhamnazin 3-O-rutinoside can be extracted from Areca catechu L. Rhamnazin 3-O-rutinoside shows no significant inhibitory effect on recombinant hPTP1B, with an IC50 > 100 μM. Rhamnazin 3-O-rutinoside reduces Apoptotic cell death. Rhamnazin 3-O-rutinoside possesses cellular antioxidant activity and alleviates H2O2-induced oxidative stress. Rhamnazin 3-O-rutinoside lacks free radical scavenging activity. Rhamnazin 3-O-rutinoside can be used in the research of neurodegenerative diseases [1] .
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