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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
hereditary copper
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "hereditary copper" in MCE Product Catalog:
134
Research Areas:
Elesclomol (STA-4783) is a potent copper ionophore and promotes copper-dependent cell death (cuproptosis). Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand. Elesclomol inhibits FDX1-mediated Fe-S cluster biosynthesis. Elesclomol is an oxidative stress inducer that induces cancer cell apoptosis. Elesclomol is a reactive oxygen species (ROS) inducer. Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research .
Ceruloplasmin is a copper-binding ferroxidase and serum copper carrier. Ceruloplasmin promotes FPN1-mediated iron export by catalyzing ferrous iron oxidation, maintains the protein stability of ferroportin, and assists transferrin and lactoferrin in completing iron binding; it regulates HIF, AMPK, PPARα, and PGC1α, exerting antioxidant effects and inhibiting ferroptosis (Ferroptosis). Ceruloplasmin can be used in research on posthemorrhagic anemia, hemolytic anemia, neurodegenerative diseases, NAFLD, metabolic diseases, hereditary aceruloplasminemia, hepatocellular carcinoma, and ischemia-reperfusion injury .
Cat. No.: HY-12040S
Synonyms: STA-4783-d2
Cat. No.: HY-12040R
CAS No.: 488832-69-5
Synonyms: STA-4783 (Standard)
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Elesclomol (Standard) is the analytical standard of Elesclomol (HY-12040). This product is intended for research and analytical applications. Elesclomol (STA-4783) is a potent copper ionophore and promotes copper-dependent cell death (cuproptosis). Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand. Elesclomol inhibits FDX1-mediated Fe-S cluster biosynthesis. Elesclomol is an oxidative stress inducer that induces cancer cell apoptosis. Elesclomol is a reactive oxygen species (ROS) inducer. Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
