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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
226 Results for "
herpes
" in MedChemExpress (MCE) Product Catalog:
Products (226)
226 Results for "herpes" in MCE Product Catalog:
33
33 Publications Verification
Synonyms: BW 759; 2'-Nor-2'-deoxyguanosine
Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
33
33 Publications Verification
Synonyms: BW 759 sodium; 2'-Nor-2'-deoxyguanosine sodium
Ganciclovir (BW 759) sodium, a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir sodium also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir sodium inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir sodium has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain .
17
Target:
Cidofovir (GS 0504) is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer . Cidofovir also has anti-orthopoxvirus and anti-variola activities .
17
17 Cited Publications
Cat. No.: HY-N6733
CAS No.: 38966-21-1
17
17 Cited Publications
Cat. No.: HY-17438A
CAS No.: 149394-66-1
Synonyms: GS 0504 dihydrate; HPMPC dihydrate; (S)-HPMPC dihydrate
13
13 Cited Publications
Synonyms: 5-Iodo-2′-deoxyuridine; 5-IUdR; IdUrd
Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM . Idoxuridine shows anti-orthopoxvirus activity.
12
12 Cited Publications
Target:
Research Areas:
ML324 is a potent JMJD2 demethylase inhibitor with antiviral activity. ML324 also exhibits inhibition for the histone demethylase KDM4B, with an IC50 of 4.9 μM. ML324 has potent anti-viral activity against both herpes simplex virus (HSV) and human cytomegalovirus (hCMV) infection via inhibition viral IE gene expression .
10
10 Cited Publications
Synonyms: CMX001; HDP-CDV
Target:
Research Areas:
Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo .
9
Category:
Cardiovascular Disease Microorganisms Animals Amino acids Disease Research Fields Inflammation/Immunology Endocrinology
Target:
9
Category:
Anti-aging Endocrine diseases Amino acids Endogenous metabolite Microorganisms Disease markers Nervous System Disorder Disease Research Fields Inflammation/Immunology Cancer
Target:
8
8 Cited Publications
Synonyms: Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine
8
8 Cited Publications
Cat. No.: HY-N6666
CAS No.: 24356-66-9
Research Areas:
Vidarabine monohydrate is a Purine nucleoside derivative and Antiviral agent. The triphosphate derivative of Vidarabine monohydrate competitively inhibits DNA polymerase, incorporates into the terminus of elongating DNA molecules, and interferes with the early steps of viral DNA synthesis. Vidarabine monohydrate inhibits the replication of herpes simplex virus, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and vaccinia virus, reduces viral shedding, and accelerates skin healing. Vidarabine monohydrate is metabolized to arabinosyl hypoxanthine, causes minimal impairment of corneal wound healing in rabbit models, and is associated with recurrence of herpes simplex encephalitis. Vidarabine monohydrate can be used in the research of herpetic keratoconjunctivitis, herpes simplex encephalitis, herpetic uveitis, and chronic active hepatitis associated with hepatitis B virus .
7
7 Cited Publications
Synonyms: AIC316; BAY 57-1293
Target:
Research Areas:
Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
7
7 Cited Publications
Synonyms: AIC316 mesylate; BAY 57-1293 mesylate
Target:
Research Areas:
Pritelivir mesylate (BAY 57-1293 mesylate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
7
7 Cited Publications
Synonyms: AIC316 mesylate hydrate; BAY 57-1293 mesylate hydrate
Target:
Research Areas:
Pritelivir mesylate hydrate (BAY 57-1293 mesylate hydrate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate hydrate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2 .
4
4 Cited Publications
Cat. No.: HY-N0772
CAS No.: 24699-16-9
3
Target:
2
2
2 Cited Publications
Cat. No.: HY-P74478
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: USP7; HAUSP; Ubiquitin Specific Peptidase 7; Ubiquitin-Specific-Processing Protease 7; Ubiquitin Carboxyl-Terminal Hydrolase 7; Deubiquitinating Enzyme 7; Ubiquitin Thioesterase 7; Ubiquitin Specific Peptidase 7 (herpes Virus-Associated); herpesvirus-Asso
Species:
Human
Source:
Sf9 insect cells
2
2 Cited Publications
Cat. No.: HY-P73837
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF14; Tumor Necrosis Factor Ligand Superfamily Member 14; TNF Superfamily Member 14; herpesvirus Entry Mediator Ligand; LIGHT; HVEML; HVEM-L; Tumor Necrosis Factor Superfamily Member 14; CD258; herpes Virus Entry Mediator Ligand; LTg; Tumor Necrosis Fa
Species:
Mouse
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
