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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
human Lyn
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "human Lyn" in MCE Product Catalog:
5
Masitinib (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib (AB1010) has anti-proliferative, pro-apoptotic activity and low toxicity .
5
5 Cited Publications
Synonyms: AB-1010 mesylate
Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity .
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Cat. No.: HY-RS07913
Target:
Research Areas:
LYN Human Pre-designed siRNA Set A contains three designed siRNAs for LYN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-10209R
CAS No.: 790299-79-5
Synonyms: AB1010 (Standard)
Masitinib (Standard) is the analytical standard of Masitinib. This product is intended for research and analytical applications. Masitinib (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib (AB1010) has anti-proliferative, pro-apoptotic activity and low toxicity .
Cat. No.: HY-10209AR
CAS No.: 1048007-93-7
Synonyms: AB-1010 mesylate (Standard)
Masitinib (mesylate) (Standard) is the analytical standard of Masitinib (mesylate). This product is intended for research and analytical applications. Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity .
Cat. No.: HY-N2259R
CAS No.: 19431-84-6
Synonyms: (+)-Curcumenol (Standard)
Cat. No.: HY-P991417
Cat. No.: HY-P73283
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Lyn; Tyrosine-Protein Kinase Lyn; Lyn Proto-Oncogene, Src Family Tyrosine Kinase; P53Lyn; JTK8; P56Lyn; V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog; Tyrosine-Protein Kinase; Lck/Yes-Related Novel Protein Tyrosine Kinase; SAIDV
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706066
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Lyn; Tyrosine-Protein Kinase Lyn; Lyn Proto-Oncogene, Src Family Tyrosine Kinase; P53Lyn; JTK8; P56Lyn; V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog; Tyrosine-Protein Kinase; Lck/Yes-Related Novel Protein Tyrosine Kinase; SAIDV
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P70289
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HCLS1; CTTNL; Hematopoietic Cell-Specific Lyn Substrate 1; Hematopoietic Cell-Specific Lyn Substrate 1; HS1; P75; Hematopoietic Lineage Cell-Specific Protein; Cortactin-Like; LckBP1
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
