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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
human PCNA
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "human PCNA" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P73729
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PCNA; Truncated Proliferating Cell Nuclear Antigen; Proliferating Cell Nuclear Antigen; DNA Polymerase Delta Auxiliary Protein; DNA Sliding Clamp PCNA; ATLD2; Cyclin
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-125576
CAS No.: 26034-16-2
Cat. No.: HY-RS10159
Target:
Research Areas:
PCNA Human Pre-designed siRNA Set A contains three designed siRNAs for PCNA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P86534
Synonyms: ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; PCNA; PCNA/cyclin; PCNA_human; PCNAR; Polymerase delta accessory protein; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03
Cat. No.: HY-P75900
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PCLAF; Overexpressed In Anaplastic Thyroid Carcinoma 1; Prev. KIAA0101; PCNA-Clamp-Associated Factor; PCNA-Associated Factor; P15PAF; NS5ATP9; PAF; OEATC-1; P15/PAF; PAF15; OEATC1; PCNA-Associated Factor Of 15 KDa; OEATC; P15(PAF); L5; Hepatitis C Virus N
Species:
Human
Source:
E. coli
Cat. No.: HY-183581
CAS No.: 3064481-29-1
Target:
Research Areas:
USP1-IN-18 is an orally active USP1 inhibitor with a human IC50 of 17.0 nM. USP1-IN-18 inhibits USP1-UAF1 deubiquitinase activity and drives ubiquitinated PCNA accumulation. USP1-IN-18 induces DNA damage, replication stress, and G2-M phase cell cycle arrest. USP1-IN-18 can be used for the research of triple-negative breast cancer .
Cat. No.: HY-183363
Target:
Research Areas:
USP1-IN-17 is an orally active USP1/UAF1 complex inhibitor. USP1-IN-17 exhibits potent anti-proliferative activity against BRCA1-mutant human breast cancer MDA-MB-436 cells, with an IC50 value of 8.1 nM. USP1-IN-17 binds to USP1 to stabilize the enzyme conformation, impairs deubiquitination function, elevates the monoubiquitination level of PCNA, inhibits cancer cell proliferation, and induces DNA damage accumulation. USP1-IN-17 can be used for the research of BRCA1-mutated cancers .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
