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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
76 Results for "
human mast cell
" in MedChemExpress (MCE) Product Catalog:
Products (76)
76 Results for "human mast cell" in MCE Product Catalog:
8
8 Publications Verification
Synonyms: C48/80 trihydrochloride
Target:
Research Areas:
Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde. Compound 48/80 trihydrochloride is also a histamine releaser and a mast cell degranulator. Compound 48/80 inhibits phosphatidylinositol-specific phospholipase C activity from human platelets .
6
6 Cited Publications
Cat. No.: HY-N0762
CAS No.: 31524-62-6
6
6 Cited Publications
Cat. No.: HY-P70781
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KITLG; SLF; Prev. MGF; Familial Progressive Hyperpigmentation 2; SCF; Steel Factor; mast cell Growth Factor; C-Kit Ligand; Stem cell Factor; Kit Ligand; DFNA69; SHEP7; Kitl; DCUA; KL-1; FPHH; FPH2; WS2F; KIT Ligand; SF
Species:
Human
Source:
E. coli
4
Target:
Research Areas:
Timapiprant (OC000459) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist. Timapiprant (OC000459) potently displaces [ 3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), and human native DP2 (Ki=4 nM). Timapiprant (OC000459) inhibits mast cell activation of Th2 lymphocytes and eosinophils .
4
4 Cited Publications
Synonyms: OC000459 sodium
Target:
Research Areas:
Timapiprant sodium (OC000459 sodium) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist. Timapiprant sodium (OC000459 sodium) potently displaces [ 3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), and human native DP2 (Ki=4 nM). Timapiprant sodium (OC000459 sodium) inhibits mast cell activation of Th2 lymphocytes and eosinophils .
4
4 Cited Publications
Cat. No.: HY-P70576
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL3; Colony-Stimulating Factor, Multiple; Interleukin 3; P-cell Stimulating Factor; IL-3; P-cell-Stimulating Factor; Hematopoietic Growth Factor; mast-cell Growth Factor; MCGF; mast cell Growth Factor; Multipotential Colony-Stimulating Factor; MGC79398; I
Species:
Human
Source:
E. coli
3
3 Cited Publications
Synonyms: NF 113; SAP 113; Methylmercadone
Research Areas:
Nifuratel (NF 113) is an orally active broad-spectrum antibiotic with antiprotozoal, antibacterial, anticancer and anti-inflammatory activities, and has good inhibitory effects on Candida and Trichomonas. Nifuratel is also a STAT3 inhibitor, which significantly inhibits the growth and proliferation of human gastric cancer cells and induces apoptosis. In addition, Nifuratel also inhibits mast cell-mediated antigen hypersensitivity reactions and can be used in the study of IgE-mediated allergic diseases .
1
1
1 Cited Publications
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ER-27319, an acridone derivative, is a potent and selective SYK inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM and can be used for study in allergic diseases .
1
1 Cited Publications
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Research Areas:
ER-27319 (maleate), an acridone derivative, is a potent and selective SKY inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 (maleate) inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM and can be used for study in allergic diseases [1] [2] .
1
1 Cited Publications
Cat. No.: HY-P7040A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL3; Colony-Stimulating Factor, Multiple; Interleukin 3; P-cell Stimulating Factor; IL-3; P-cell-Stimulating Factor; Hematopoietic Growth Factor; mast-cell Growth Factor; MCGF; mast cell Growth Factor; Multipotential Colony-Stimulating Factor; MGC79398; I
Species:
Human
Source:
CHO
1
1 Cited Publications
Cat. No.: HY-P70765
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL3; Colony-Stimulating Factor, Multiple; Interleukin 3; P-cell Stimulating Factor; IL-3; P-cell-Stimulating Factor; Hematopoietic Growth Factor; mast-cell Growth Factor; MCGF; mast cell Growth Factor; Multipotential Colony-Stimulating Factor; MGC79398; I
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P7046
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL9; Homolog Of Mouse T cell And mast cell Growth Factor 40; Interleukin 9; P40 T-cell And mast cell Growth Factor; IL-9; Interleukin-9; T-cell Growth Factor P40; P40 Cytokine; HP40; Cytokine P40; P40
Species:
Human
Source:
CHO
1
1 Cited Publications
Cat. No.: HY-P70757G
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KITLG; SLF; Prev. MGF; Familial Progressive Hyperpigmentation 2; SCF; Steel Factor; mast cell Growth Factor; C-Kit Ligand; Stem cell Factor; Kit Ligand; DFNA69; SHEP7; Kitl; DCUA; KL-1; FPHH; FPH2; WS2F; KIT Ligand; SF
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P76059
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SRGN; Proteoglycan 1, Secretory Granule; Prev. PRG1; P.PG; Prev. PRG; Proteoglycan Protein Core For mast cell Secretory Granule; PPG; Secretory Granule Proteoglycan Core Peptide; Secretory Granule Proteoglycan Core Protein; Hematopoetic Proteoglycan Core
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P76058
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SRGN; Proteoglycan 1, Secretory Granule; Prev. PRG1; P.PG; Prev. PRG; Proteoglycan Protein Core For mast cell Secretory Granule; PPG; Secretory Granule Proteoglycan Core Peptide; Secretory Granule Proteoglycan Core Protein; Hematopoetic Proteoglycan Core
Species:
Human
Source:
HEK293
Cat. No.: HY-P991636
Target:
Research Areas:
Cat. No.: HY-19393
CAS No.: 444659-43-2
Target:
Research Areas:
SCH 351591 is a highly selective, orally active PDE4 inhibitor, with IC50 values of 58 nM and 153 nM in humans and rats, respectively. SCH 351591 effectively inhibits pathological processes such as cytokine production, eosinophilia, airway hyperresponsiveness and bronchospasm. SCH 351591 also induces microvascular injury, activates mast cells and endothelial cells, and causes increases in serum histamine and various inflammatory factors, leading to early vascular damage. SCH 351591 has been widely used in studies related to asthma, chronic obstructive pulmonary disease and drug-induced vascular injury .
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Research Areas:
Bufrolin is a Cromoglycate (histamine release inhibitor) analog and a high potency agonist of GPR35. Bufrolin promotes interactions between β-arrestin-2 and either human GPR35a or rat GPR35. Bufrolin also serves as antiallergic mast cell stabilizer and inhibit an anti-inflammatory response inducible by the internalization peptide. Bufrolin acts as an anti-inflammatory agent to be used in research of delivering pharmacol linked with internalization peptide .
Cat. No.: HY-100269
CAS No.: 862090-74-2
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Chymase-IN-1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
